Abstract:Age related macular degeneration (AMD) is a common multifactorial disease among the elderly, which may lead to irreversible vision loss; However, the pathogenesis of AMD is still unclear. Metabolomics is a relatively new "omics" technique that can provide qualitative and quantitative information about low molecular weight metabolites in a given biological system, thereby revealing the physiological or pathological state of cell or tissue samples at specific time points. The retina is one of the most metabolically active tissues in the human body, so using metabolomics techniques to measure molecular changes in AMD will further enhance our understanding of the pathogenesis. This will provide important insights for the prevention and treatment of AMD, This article reviews the application of metabolomics in AMD.
