Application of perceptual learning in amblyopia treatment
Author:
  • Xiao-Tong Wu

    Xiao-Tong Wu

    Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China; Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine;Eye Institute of Shandong University of Traditional Chinese Medicine;Shandong Provincial Key Laboratory of Integrative Medicine for Eye Diseases;Shandong Provincial Clinical Research Center of Ophthalmology and Children Visual Impairment Prevention and Control;Shandong Engineering Technology Research Center of Visual Intelligence;Shandong Institute of Children Health and Myopia Prevention and Control, Jinan 250002, Shandong Province, China
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  • Ai-Ling Bi

    Ai-Ling Bi

    Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine;Eye Institute of Shandong University of Traditional Chinese Medicine;Shandong Provincial Key Laboratory of Integrative Medicine for Eye Diseases;Shandong Provincial Clinical Research Center of Ophthalmology and Children Visual Impairment Prevention and Control;Shandong Engineering Technology Research Center of Visual Intelligence;Shandong Institute of Children Health and Myopia Prevention and Control, Jinan 250002, Shandong Province, China
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  • Xiu-Zhen Lu

    Xiu-Zhen Lu

    Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China; Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine;Eye Institute of Shandong University of Traditional Chinese Medicine;Shandong Provincial Key Laboratory of Integrative Medicine for Eye Diseases;Shandong Provincial Clinical Research Center of Ophthalmology and Children Visual Impairment Prevention and Control;Shandong Engineering Technology Research Center of Visual Intelligence;Shandong Institute of Children Health and Myopia Prevention and Control, Jinan 250002, Shandong Province, China
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  • Hong-Sheng Bi

    Hong-Sheng Bi

    Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China; Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine;Eye Institute of Shandong University of Traditional Chinese Medicine;Shandong Provincial Key Laboratory of Integrative Medicine for Eye Diseases;Shandong Provincial Clinical Research Center of Ophthalmology and Children Visual Impairment Prevention and Control;Shandong Engineering Technology Research Center of Visual Intelligence;Shandong Institute of Children Health and Myopia Prevention and Control, Jinan 250002, Shandong Province, China
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Fund Project:

National Key Research and Development Program(No.2019YFC1710200)

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    Abstract:

    Amblyopia is a common eye disease in children. In recent years, people have been exploring new treatments for amblyopia patients with poor results of the traditional treatment. In the field of visual cognition, some computer programs and video games are widely used to improve the functions of the visual system. Based on the perceptual learning, new methods such as video games, dichotomous stimulation, and stereo vision training are proposed to treat amblyopia. This article combines domestic and foreign research on perceptual learning and other emerging methods. The application of therapies in the treatment of amblyopia was reviewed, the effects of different methods in the treatment of amblyopia were analyzed. Combined with the existing problems, the future development of this field was further discussed.

    Reference
    1中华医学会眼科学分会斜视与小儿眼科学组, 中国医师协会眼科医师分会斜视与小儿眼科学组. 中国儿童弱视防治专家共识(2021年). 中华眼科杂志 2021; 57(5):336-340
    2 Fu ZJ, Hong H, Su ZC, et al. Global prevalence of amblyopia and disease burden projections through 2040:a systematic review and meta-analysis. Br J Ophthalmol 2020; 104(8):1164-1170
    3 Wallace DK, Repka MX, Lee KA, et al. Amblyopia preferred practice pattern®. Ophthalmology 2018; 125(1):105-142
    4 DeSantis D. Amblyopia. Pediatr Clin North Am 2014; 61(3):505-518
    5 Ahmadi M, McDevitt EA, Silver MA, et al. Perceptual learning induces changes in early and late visual evoked potentials. Vision Res 2018; 152:101-109
    6 Deveau J, Seitz AR. Applying perceptual learning to achieve practical changes in vision. Front Psychol 2014; 5:1166
    7 Hernández-Rodríguez CJ, Piñero DP, Molina-Martín A, et al. Stimuli characteristics and psychophysical requirements for visual training in amblyopia: a narrative review. J Clin Med 2020; 9(12): 3985
    8 Hussain Z, Webb BS, Astle AT, et al. Perceptual learning reduces crowding in amblyopia and in the normal periphery. J Neurosci 2012; 32(2):474-480
    9 Zhang WQ, Yang XB, Liao M, et al. Internet-based perceptual learning in treating amblyopia. Eur J Ophthalmol 2013; 23(4):539-545
    10 Gu L, Deng SY, Feng L, et al. Effects of monocular perceptual learning on binocular visual processing in adolescent and adult amblyopia. iScience 2020; 23(2):100875
    11 Portela-Camino JA, Martín-González S, Ruiz-Alcocer J, et al. Predictive factors for the perceptual learning in stereodeficient subjects. J Optom 2021; 14(2):156-165
    12 Falcone MM, Hunter DG, Gaier ED. Emerging therapies for amblyopia. Semin Ophthalmol 2021; 36(4):282-288
    13 Levi DM. Rethinking amblyopia 2020. Vision Res 2020; 176:118-129
    14 Levi DM. Prentice award lecture 2011:removing the brakes on plasticity in the amblyopic brain. Optom Vis Sci 2012; 89(6):827-838
    15 Singh A, Sharma P, Saxena R. Evaluation of the role of monocular video game play as an adjuvant to occlusion therapy in the management of anisometropic amblyopia. J Pediatr Ophthalmol Strabismus 2017; 54(4):244-249
    16 Li RW, Young KG, Hoenig P, et al. Perceptual learning improves visual performance in juvenile amblyopia. Invest Ophthalmol Vis Sci 2005; 46(9):3161-3168
    17 de Kloet ER, Joëls M, Holsboer F. Stress and the brain: from adaptation to disease. Nat Rev Neurosci 2005; 6(6):463-475
    18 Bavelier D, Green CS, Pouget A, et al. Brain plasticity through the life span: learning to learn and action video games. Annu Rev Neurosci 2012; 35:391-416
    19 Dadeya S, Dangda S. Television video games in the treatment of amblyopia in children aged 4-7 years. Strabismus 2016; 24(4):146-152
    20 Lee HJ, Kim SJ. Outcomes of using Bangerter foils for the treatment of residual amblyopia following patching therapy. Graefes Arch Clin Exp Ophthalmol 2021; 259(10):3167-3174
    21 Kelly KR, Jost RM, Dao L, et al. Binocular iPad game vs patching for treatment of amblyopia in children: a randomized clinical trial. JAMA Ophthalmol 2016; 134(12):1402-1408
    22 Birch EE, Jost RM, Kelly KR, et al. Baseline and clinical factors associated with response to amblyopia treatment in a randomized clinical trial. Optom Vis Sci 2020; 97(5):316-323
    23 Holmes JM, Manh VM, Lazar EL, et al. Effect of a binocular iPad game vs part-time patching in children aged 5 to 12 years with amblyopia: a randomized clinical trial. JAMA Ophthalmol 2016; 134(12):1391-1400
    24 Manh VM, Holmes JM, Lazar EL, et al. A randomized trial of a binocular iPad game versus part-time patching in children aged 13 to 16 years with amblyopia. Am J Ophthalmol 2018; 186:104-115
    25 Birch EE, Jost RM, De la Cruz A, et al. Binocular amblyopia treatment with contrast-rebalanced movies. J AAPOS 2019; 23(3):160.e1-160.e5
    26 Bossi M, Tailor VK, Anderson EJ, et al. Binocular therapy for childhood amblyopia improves vision without breaking interocular suppression. Invest Ophthalmol Vis Sci 2017; 58(7):3031-3043
    27 Mezad-Koursh D, Rosenblatt A, Newman H, et al. Home use of binocular dichoptic video content device for treatment of amblyopia: a pilot study. J AAPOS 2018; 22(2):134-138.e4
    28 Coco-Martin MB, Piñero DP, Leal-Vega L, et al. The potential of virtual reality for inducing neuroplasticity in children with amblyopia. J Ophthalmol 2020; 2020:7067846
    29 Herbison N, MacKeith D, Vivian A, et al. Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system. Br J Ophthalmol 2016; 100(11):1511-1516
    30 Rajavi Z, Sabbaghi H, Amini Sharifi E, et al. The role of Interactive Binocular Treatment system in amblyopia therapy. J Curr Ophthalmol 2016; 28(4):217-222
    31 Rajavi Z, Sabbaghi H, Amini Sharifi E, et al. Comparison between patching and interactive binocular treatment in amblyopia: a randomized clinical trial. J Curr Ophthalmol 2019; 31(4):426-431
    32 Gambacorta C, Nahum M, Vedamurthy I, et al. An action video game for the treatment of amblyopia in children: a feasibility study. Vision Res 2018; 148:1-14
    33 Vedamurthy I, Nahum M, Huang SJ, et al. A dichoptic custom-made action video game as a treatment for adult amblyopia. Vision Res 2015; 114:173-187
    34 Li JR, Spiegel DP, Hess RF, et al. Dichoptic training improves contrast sensitivity in adults with amblyopia. Vision Res 2015; 114:161-172
    35 Martín-González S, Portela-Camino J, Ruiz-Alcocer J, et al. Stereoacuity improvement using random-dot video games. J Vis Exp 2020(155):10.3791/60236
    36 Vedamurthy I, Knill DC, Huang SJ, et al. Recovering stereo vision by squashing virtual bugs in a virtual reality environment. Philos Trans R Soc Lond B Biol Sci 2016; 371(1697):20150264
    37 Li RW, Tran KD, Bui JK, et al. Improving adult amblyopic vision with stereoscopic 3-dimensional video games. Ophthalmology 2018; 125(10):1660-1662
    38 Li RW, Ngo C, Nguyen J, et al. Video-game play induces plasticity in the visual system of adults with amblyopia. PLoS Biol 2011; 9(8):e1001135
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Xiao-Tong Wu, Ai-Ling Bi, Xiu-Zhen Lu,/et al.Application of perceptual learning in amblyopia treatment. Guoji Yanke Zazhi( Int Eye Sci) 2022;22(6):951-954

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Publication History
  • Received:September 03,2021
  • Revised:April 28,2022
  • Online: May 30,2022