Differences in clinical characteristics and laboratory parameters of primary and recurrent pterygium
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    Abstract:

    Pterygium is a common conjunctival disease which is mainly attributed to chronic ultraviolet light exposure. Previous studies have focused primarily on the clinical characteristics, surgical management and the pathogenesis of pterygium, but the differences between primary pterygium and recurrent pterygium have been less frequently documented. This article reviews the differences in clinical manifestations, histopathological findings, and laboratory parameters between primary pterygium and recurrent pterygium and summarises the latest findings regarding these differences.

    Reference
    1 Soliman W, Mohamed TA. Spectral domain anterior segment optical coherence tomography assessment of pterygium and pinguecula. Acta Ophthalmol 2012; 90(5):461-465
    2 Ip MH, Chui JJ, Tat L, et al. Significance of Fuchs Flecks in Patients With Pterygium/Pinguecula:Earliest Indicator of Ultraviolet Light Damage. Cornea 2015; 34(12):1560-1563
    3 Ooi JL, Sharma NS, Sharma S, et al. Ultraviolet fluorescence photography:patterns in established pterygia. Am J Ophthalmol 2007; 143(1):97-101
    4 Ozgurhan EB, Kara N, Bozkurt E, et al. Comparison of conjunctival graft thickness after primary and recurrent pterygium surgery: anterior segment optical coherence tomography study. Indian J Ophthalmol 2014; 62(6):675-679
    5 Julio G, Lluch S, Pujol P, et al. Tear osmolarity and ocular changes in pterygium. Cornea 2012; 31(12):1417-1421
    6 Tan J, Vollmer-Conna U, Tat L, et al. Dry-Eye Disease in Recurrent Pterygium. Ophthalmic Res 2019; 61(4):199-203
    7 Ling S, Li Q, Lin H, et al. Comparative evaluation of lymphatic vessels in primary versus recurrent pterygium. Eye(Lond) 2012; 26(11):1451-1458
    8 Liu L, Ling SQ, Li QL, et al. Relations between lymphangiogenesis and the size of pterygium. Int J Ophthalmol 2012; 5(3):312-316
    9 Nuhoglu F, Turna F, Uyar M, et al. Is there a relation between histopathologic characteristics of pterygium and recurrence rates. Eur J Ophthalmol 2013; 23(3):303-308
    10陈祎祎, 杨桂芳. 翼状胬肉复发与病理组织变化的关系. 中国医学创新2012; 9(11):130-131
    11 Zhou WP, Zhu YF, Zhang B, et al. The role of ultraviolet radiation in the pathogenesis of pterygia(Review). Mol Med Rep 2016; 14(1):3-15
    12 Kormanovski A, Parra F, Jarillo-Luna A, et al. Oxidant/antioxidant state in tissue of prymary and recurrent pterygium. BMC Ophthalmol 2014; 14:149
    13 Kamis U, Kerimoglu H, Ozkagnici A, et al. Frequency of chromosome 17 aneuploidy in primary and recurrent pterygium by interphase-fluorescence in situ hybridization. Ophthalmic Res 2006; 38(2):89-94
    14 Cimpean AM, Sava MP, Raica M. DNA damage in human pterygium: one-shot multiple targets. Mol Vis 2013; 19:348-356
    15 Chen YT, Tseng SH, Tsai YY, et al. Distribution of vimentin-expressing cells in pterygium: an immunocytochemical study of impression cytology specimens. Cornea 2009; 28(5):547-552
    16梁坤. 肥大细胞在翼状胬肉中的作用及细胞增殖/凋亡与翼状胬肉复发的关系研究. 安徽医科大学2016
    17 Ramalho FS, Maestri C, Ramalho LN, et al. Expression of p63 and p16 in primary and recurrent pterygia. Graefes Arch Clin Exp Ophthalmol 2006; 244(10):1310-1314
    18 Zhang Y, Liu F. Elevation of S100 calcium-binding protein A7 in recurrent pterygium. Exp Ther Med 2019; 18(4):3147-3152
    19 Huang YH, Chang NS, Tseng SH. Expression of WW domain-containing oxidoreductase WWOX in pterygium. Mol Vis 2015; 21:711-717
    20 Xu K, Tao T, Jie J, et al. Increased importin 13 activity is associated with the pathogenesis of pterygium. Mol Vis 2013; 19:604-613
    21钟森全. 白介素8及骨膜蛋白在翼状胬肉中的表达及意义. 川北医学院2015
    22 Dinç E, Dursun Ö, Yılmaz B, et al. Expression of prostaglandin E2 receptor subtypes in human pterygium and normal conjunctiva:immunohistochemical study. Int Ophthalmol 2018; 38(4):1703-1708
    23 Adiguzel U, Karabacak T, Sari A, et al. Cyclooxygenase-2 expression in primary and recurrent pterygium. Eur J Ophthalmol 2007; 17(6):879-884
    24 Baser G, Sivrikoz ON, Karahan E, et al. The Influence of Chemokine CXCR4 and Cyclooxygenase-2 in the Recurrence of Pterygium. Ocul Immunol Inflamm 2017; 25(3):328-332
    25 Assimakopoulou M, Pagoulatos D, Nterma P, et al. Immunolocalization of cannabinoid receptor type 1 and CB2 cannabinoid receptors, and transient receptor potential vanilloid channels in pterygium. Mol Med Rep 2017; 16(4):5285-5293
    26 Xue C, Huang Z, Wang J, et al. EphrinB2 and EphB4 expression in pterygia:new insights and preliminary results. Ophthalmol 2009; 44(2):185-188
    27 Detorakis ET, Zaravinos A, Spandidos DA. Growth factor expression in ophthalmic pterygia and normal conjunctiva. Int J Mol Med 2010; 25(4):513-516
    28 Khalfaoui T, Mkannez G, Colin D, et al. Immunohistochemical analysis of vascular endothelial growth factor(VEGF)and p53 expression in pterygium from Tunisian patients. Pathol Biol(Paris) 2011; 59(3):137-141
    29 Wang Y, Lin J, Chen L, et al. Expression of Peroxiredoxin 2 and Vascular Endothelial Growth Factor Receptor 2 in Pterygium. Cornea 2017; 36(7):841-844
    30 Kria L, Ohira A, Amemiya T. Growth factors in cultured pterygium fibroblasts: immunohistochemical and ELISA analysis. Graefes Arch Clin Exp Ophthalmol 1998; 236(9):702-708
    31 Tan DT, Liu YP, Sun L, et al. Flow cytometry measurements of DNA content in primary and recurrent pterygia. Invest Ophthalmol Vis Sci 2000; 41(7):1684-1686
    32 Han YF, Liu Z, Wang B, et al. Semaphorin 7a participants in pterygium by regulating vascular endothelial growth factor. Int J Ophthalmol 2019; 12(6):892-897
    33 An MX, Wu KL, Lin SC. Detection and comparison of matrix metalloproteinase in primary and recurrent pterygium fibroblasts. Int J Ophthalmol 2011; 4(4):353-356
    34 Schellini SA, Hoyama E, Oliveira DE, et al. Matrix metalloproteinase-9 expression in pterygium. Arq Bras Oftalmol 2006; 69(2):161-164
    35 Park YM, Kim CD, Lee JS. Effect of Bevacizumab on Human Tenon's Fibroblasts Cultured from Primary and Recurrent Pterygium. Korean J Physiol Pharmacol 2015; 19(4):357-363
    36 Viveiros MM, Kakizaki FY, Hércules LA, et al. In vitro study of cyclosporine A 0.05% on primary and recurrent pterygium fibroblasts. Int Ophthalmol 2016; 36(2):237-242
    37 Lee JS, Oum BS, Lee SH. Mitomycin c influence on inhibition of cellular proliferation and subsequent synthesis of type I collagen and laminin in primary and recurrent pterygia. Ophthalmic Res 2001; 33(3):140-146
    38 Malik S, Khan MS, Basit I. Comparison of primary versus recurrent pterygium after intralesional 5-Fluorouracil. J Pak Med Assoc 2016; 66(5):559-562
    39 Chalkia AK, Bontzos G, Spandidos DA, et al. Human papillomavirus infection and ocular surface disease(Review). Int J Oncol 2019; 54(5):1503-1510
    40 Hamed-Azzam S, Edison N, Briscoe D, et al. Identification of human papillomavirus in pterygium. Acta Ophthalmol 2016; 94(3):195-197
    41 Chong PP, Tung CH, Rahman NA, et al. Prevalence and viral load of oncogenic human papillomavirus(HPV)in pterygia in multi-ethnic patients in the Malay Peninsula. Acta Ophthalmol 2014; 92(7):569-579
    42 Hsiao CH, Lee BH, Ngan KW, et al. Presence of human papillomavirus in pterygium in Taiwan. Cornea 2010; 29(2):123-127
    43 Otlu B, Emre S, Turkcuoglu P, et al. Investigation of human papillomavirus and Epstein-Barr virus DNAs in pterygium tissue. Eur J Ophthalmol 2009; 19(2):175-179
    44 He S, Sun H, Huang Y, et al. Identification and Interaction Analysis of Significant Genes and MicroRNAs in Pterygium. Biomed Res Int 2019; 2019:2767512
    45 Lee JH, Jung SA, Kwon YA, et al. Expression of microRNAs in fibroblast of pterygium. Int J Ophthalmol 2016; 9(7):967-972
    46 Li X, Dai Y, Xu J. MiR-21 promotes pterygium cell proliferation through the PTEN/AKT pathway. Mol Vis 2018; 24:485-494
    47 Lan W, Chen S, Tong L. MicroRNA-215 Regulates Fibroblast Function: Insights from a Human Fibrotic Disease. Cell Cycle 2015; 14(12):1973-1984
    48 Chien KH, Chen SJ, Liu JH, et al. Correlation of microRNA-145 levels and clinical severity of pterygia. Ocul Surf 2013; 11(2):133-138
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Yun-Zhi Shen, Mi Xu, Song Sun. ,/et al.Differences in clinical characteristics and laboratory parameters of primary and recurrent pterygium. Guoji Yanke Zazhi( Int Eye Sci) 2020;20(4):639-642

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Publication History
  • Received:August 20,2019
  • Revised:March 13,2020
  • Online: March 25,2020