Abstract:AIM: To investigate the affecting factors that can serve as prognostic indicators of treatment outcomes, providing the first hand information for decision-making in therapy of fungal keratitis.
METHODS: Totally 105 cases(105 eyes)with fungal keratitis were enrolled, characteristics at diagnosis, laboratory examinations and treatment responses were analyzed statistically to estimate the relative risk of the main prognostic variables.
RESULTS: Among the 105 cases analyzed in the study,49 eyes(46.7%)were successfully cured, 30 eyes(28.6%)had slow-healing ulcers and 26 eyes(24.8%)were refractory to primary treatment.
CONCLUSION: The predictors of treatment failure are antifungal therapy begin at more than 7 days after symptoms appeared, ulcers that exceeded 16 mm2, the presence of hypopyon that more than 2 mm and identification of Fusarium.
