Abstract:AIM:To evaluate the cause and therapy for secondary glaucoma following vitrectomy.METHODS:Twenty patients with secondary glaucoma following vitrectomy were analyzed retrospectively. In order to determine the cause of secondary glaucoma, intraocular pressure(IOP), ultrasound biomicroscopy(UBM) and chamber-angle microscopy were taken, according to the different cause of secondary glaucoma, drug or surgery was selected.RESULTS:The IOP elevation occurred mostly within two weeks to three months. The IOP was 30-50mmHg. The angle closed in 15 patients with the examination by chamber angle microscopy and UBM the others remained open. The main cause of secondary glaucoma included long-time applying topical steroid, iris neovascularization and anterior inflammation and hemorrhage.CONCLUSION:Secondary glaucoma following vitrectomy is a complicated complication. The different therapy may select according to the different cause.