Abstract:AIM:To evaluate the result of the blue light-filtering photochromics IOL Matrix Aurium and compare patient-reported vision-related function between the blue light-filtering photochromic intraocular lens and a similar clear one that does not filter blue light. METHODS:Consecutively 57 eyes selected from 49 senile cataract patients who came from Beijing Prison Administration Bureau Central Hospital in 2007- 09/2010-10 were divided into two groups by their type of IOL according to their ideal:blue light-filtering photochromics IOL Matrix Aurium groups (Matrix 400) and a clear ultraviolet-filtering IOL (Matrix 401). The patients lived in Beijing or vicinity, which can be followed up in time. All patients performed phacoemulsification and IOL implantation,complications in operation or after operation were observed, and 3 months after operation several tests were done by the same technicians.The parameters included best corrective visual acuity (BCVA) under photopic(1000lux)and mesopic(40lux) and of the same time in sunlight outdoors, subjective visual quality was assessed with the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25). Patients were investigated whether they had to wear sunglasses in sunlight outdoors. RESULTS:There were no other complications in or after operation except several mild corneal edema. We could observe that the blue light-filtering photochromics IOL Matrix Aurium could turn yellow in sunlight outdoors, about 6.5% patients needed a sunglass in Matrix 400 group, which was significantly lower than 30.8% in Matrix 401 group(P=0.032).There were no significant difference in BCVA under photopic(1000lux) or mesopic(40lux) or outdoors between two groups (P>0.05). There were no significant difference in mean NEI VFQ-25 scores. CONCLUSION:Blue light-filtering photochromics IOL Matrix Aurium has fuction of turning yellow in human’s eyes,povides good vision, and reduce the rate wearing sunglass in sunlight outdoors.Its retinal protective effects are needed for further study.
