Abstract:AIM: To evaluate the differences and agreement among five ophthalmic devices including calipers, Pentacam HR, IOL Master 700, OPD Scan Ⅲ, and CIRRUS HD-OCT in measuring the corneal white-to-white(WTW)diameter prior to implantable collamer lens(ICL)implantation, and to provide evidence for optimal ICL size selection.
METHODS:This retrospective study included high myopia patients who underwent ICL V4c implantation in the hospital between November 2023 and June 2024. Preoperative WTW measurements were obtained using calipers, Pentacam HR, IOL Master 700, OPD Scan Ⅲ, and CIRRUS HD-OCT. Differences and agreement of measurements among the devices were compared.
RESULTS:A total of 249 high myopia patients(498 eyes)were enrolled in this study, including 85 males(170 eyes)and 164 females(328 eyes). The patients' age ranged from 18 to 38 y, with a mean age of 30.2±5.8 y. The mean WTW values measured by calipers, Pentacam HR, IOL Master 700, OPD Scan Ⅲ, and CIRRUS HD-OCT were 11.24±0.31, 11.55±0.35, 11.88±0.37, 11.69±0.38, and 11.56±0.41 mm, respectively. No significant difference was found between Pentacam HR and CIRRUS HD-OCT(P>0.05), while significant differences were observed among all other measurement method pairs(P<0.05). All measurement methods showed significant positive correlations(P<0.01). Bland-Altman analysis demonstrated that only the comparison between Pentacam HR and OPD Scan Ⅲ, Pentacam HR and CIRRUS HD-OCT, and OPD Scan Ⅲ and IOL Master 700 had 95% limits of agreement within ±0.50 mm.
CONCLUSION:Systematic differences exist among the five devices in measuring WTW, with IOL Master 700 yielding the largest value and caliper the smallest. Caliper measurements demonstrate poor agreement with automated devices and should not be considered interchangeable. In contrast, Pentacam HR, OPD Scan Ⅲ, and CIRRUS HD-OCT, OPD Scan Ⅲ and IOL Master 700 demonstrate relatively good agreement and may serve as alternative references for ICL sizing in clinical practice.
