Advances in carotid artery stenosis and ocular ischemic diseases
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Top Talent Support Program for “Double Hundred”Young and Middle-aged People of Wuxi Health Committee(No.BJ2023037); the Scientific Research and Development Public Welfare Program of the China Health Promotion Foundation(No.2025-ZCXY-0455).

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    Abstract:

    Carotid artery stenosis(CAS)can significantly impair ocular hemodynamics, resulting in ischemic injury involving the retina, choroid, and optic nerve. The severity of CAS can be accurately evaluated using multimodal imaging techniques, including carotid ultrasonography and magnetic resonance angiography. Moderate to severe CAS is closely associated with ocular ischemic syndrome, retinal arterial and venous occlusions, retinal structural alterations(such as retinal ischemic perivascular lesions, thinning of the retinal nerve fiber layer, and subretinal drusenoid deposits), ischemic optic neuropathy, and changes in choroidal blood flow. Carotid endarterectomy and carotid artery stenting may improve ocular perfusion and alleviate ischemic manifestations; however, postoperative complications such as retinal artery embolism require careful monitoring. This review summarizes recent advances in the understanding of the relationship between CAS and ocular ischemic diseases.

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Wei Shanxin, Zhang Zhengwei. Advances in carotid artery stenosis and ocular ischemic diseases. Guoji Yanke Zazhi( Int Eye Sci) 2026;26(6):1012-1016

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Publication History
  • Received:November 13,2025
  • Revised:April 23,2026
  • Adopted:
  • Online: May 18,2026
  • Published: