Abstract:Retinal vein occlusion(RVO)is the second most common retinal vascular disease in China and is frequently accompanied by systemic cardiovascular and cerebrovascular disorders. Dyslipidemia serves as a key risk factor for RVO. Dyslipidemia drives the progression of RVO through multiple pathological mechanisms, including vascular endothelial injury, hemodynamic abnormalities, oxidative stress, and inflammatory responses. It is also closely associated with complications such as macular edema and neovascularization. This review systematically summarizes current research on the role of dyslipidemia in the pathogenesis of RVO and its clinical significance. By analyzing the associations between lipid profile indicators and RVO, this article aims to emphasize the importance of managing primary diseases and systemic risk factors, and to provide a theoretical basis for early comprehensive systemic interventions targeting dyslipidemia in patients with RVO.