Clinical study of the protective effect of a novel anti-blue light film against visual fatigue
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Zhejiang Provincial Medical and Health Technology Plan(No.2023KY1141); Ningbo Natural Science Foundation(No. 2023J212)

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    Abstract:

    AIM: To evaluate the clinical efficacy of a novel anti-blue light film in alleviating dry eye symptoms, improving visual function, and reducing visual fatigue.

    METHODS: This study was a prospective trial. From April 2023 to March 2024, participants meeting the inclusion criteria were recruited from Ningbo Eye Hospital. They were randomly divided using a random number table into a novel anti-blue light film group, an ordinary anti-blue light film group, and a transparent film group without blue-light filtering properties. After intervention for 3 mo, tear film break-up time(BUT), accommodative facility, accommodative amplitude, and visual fatigue scores were compared among the three groups before and after the intervention.

    RESULTS: A total of 82 participants(164 eyes)were included in this study, comprising 26 participants(52 eyes)in the novel anti-blue light film group, 26 participants(52 eyes)in the ordinary anti-blue light film group, and 30 participants(60 eyes)in the transparent film group without blue-light filtering properties. All participants completed the entire study with no loss to follow-up. After the 3-month intervention, the BUT of both the left and right eyes in the novel anti-blue light film group was significantly prolonged compared to before the intervention(all P<0.05), and the BUT of right eyes was superior to those in both the ordinary anti-blue light film group and the transparent film group without blue-light filtering properties(all P<0.05). After the 3-month intervention, the right eye accommodative facility and the accommodative amplitude of both eyes in the novel anti-blue light film group improved(P<0.05); the accommodative facility of both eyes in the ordinary anti-blue light film group significantly worsened(P<0.05). The visual fatigue score increased in the ordinary anti-blue light film group(P<0.001), while no significant changes were observed before and after intervention in the transparent film group without blue-light filtering properties or the novel anti-blue light film group.

    CONCLUSION: The novel anti-blue light film can effectively prolong tear film BUT and improve accommodative function, but its effect on alleviating visual fatigue is limited; the ordinary film exacerbates visual fatigue and impairs visual function.

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Gong Yan, Li Meng, Zhang Keke, et al. Clinical study of the protective effect of a novel anti-blue light film against visual fatigue. Guoji Yanke Zazhi( Int Eye Sci) 2026;26(2):347-352

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Publication History
  • Received:September 17,2025
  • Revised:December 29,2025
  • Adopted:
  • Online: January 14,2026
  • Published: