Advances in the application of in vivo confocal microscopy on bulbar conjunctival diseases
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National Natural Science Foundation of China(No.82171038); Scientific Research of Jiangsu Commission of Health(No.M2021084); Jiangsu Province Graduate Student Scientific Research and Practice Innovation Program(No.SJCX24_2046); Nantong Science and Technology Project(No.MS22022020)

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    Abstract:

    In vivo confocal microscopy(IVCM)is a real-time and non-invasive imaging technology that allows for the evaluation of morphological changes in ocular surface tissues under both physiological and pathological conditions. It offers detailed and cellular-level insight into the microscopic architecture of the ocular surface. In recent years, a growing body of research has incorporated IVCM into the study of bulbar conjunctival diseases. By providing high-resolution imaging and quantitative analysis of cellular features, IVCM not only offers novel insights into the mechanisms underlying these diseases but also supplies valuable longitudinal data for clinical diagnosis, treatment, and therapeutic evaluation. Therefore, this review elucidates the current applications, limitations and future clinical potential of IVCM in bulbar conjunctival diseases, with the aim of providing theoretical reference and practical guidance for clinical practice.

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Dai Yuxin, Li Pengfei, Wang Rong, et al. Advances in the application of in vivo confocal microscopy on bulbar conjunctival diseases. Guoji Yanke Zazhi( Int Eye Sci) 2026;26(2):243-247

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Publication History
  • Received:June 27,2025
  • Revised:December 19,2025
  • Adopted:
  • Online: January 14,2026
  • Published: