Abstract:Objective: To evaluate the application value of contrast-enhanced ultrasound (CEUS) time parameters in the typing diagnosis of choroidal space-occupying lesions. Methods: A total of 120 patients with choroidal space-occupying lesions who underwent CEUS at Xi"an People"s Hospital (Xi"an Fourth Hospital) from June 2020 to January 2024 were selected. Based on the final clinical and pathological diagnoses, patients were divided into three groups: benign (choroidal hemangioma), malignant (choroidal melanoma), and hemorrhage (subchoroidal hemorrhage), with 40 cases in each group. The characteristics of CEUS, contrast parameters (such as time to fill, time to peak, and washout time), and the incidence of adverse reactions were analyzed to evaluate the diagnostic efficacy. Results: The benign group showed homogeneous high perfusion, presenting a "fast-in and slow-out" perfusion mode. The malignant group predominantly showed heterogeneous high perfusion, presenting a "fast-in and fast-out" perfusion mode. The hemorrhage group showed no significant perfusion, presenting a "no-in and no-out" perfusion mode. Significant differences were found in the CEUS characteristics and parameters among the three groups, while there was no significant difference in the incidence of adverse reactions. Conclusion: CEUS can significantly improve the diagnostic accuracy of choroidal space-occupying lesions, providing important reference value for clinical practice and demonstrating a high safety profile.
