Abstract:Abstract Objective: To observe the clinical efficacy of preoperative comprehensive treatment in cataract patients with diabetes. Methods: 60 patients who were admitted to our hospital from May 2023 to December 2024 and were diagnosed as cataract complicated with diabetes by slit lamp microscopy, Schirmer test, clinical symptoms, laboratory tests, etc., and had different degrees of dry eye symptoms at the same time, were selected as the research objects. According to different preoperative dry eye treatment schemes, the patients were divided into two groups: the control group (30 cases) received only eye medication [artificial tears], and the experimental group (30 cases) received comprehensive preoperative dry eye treatment [artificial tears+meibomian gland clean massage+Chinese medicine fumigation+health guidance]. The tear film rupture time (BUT), corneal fluorescence staining (FL), ocular surface disease index (OSDI) score, tear river height (TMH) and non-invasive tear film rupture time (NIBUT) were compared between the two groups before and after 4 weeks of treatment, and the meibomian gland loss, tear film lipid layer thickness and basic eye symptoms were evaluated. Results: After 4 weeks of preoperative treatment, the BUT of the experimental group increased from (4.09± 1.13) s to (10.35± 1.46) s, and that of the control group increased from (4.15 ±1.05) s to (8.26 ±1.36) s, with significant differences between the two groups (t=5.737, P < 0.001). The FL score of the experimental group decreased from (6.83± 0.46) to (2.86± 0.38), and that of the control group decreased from (6.79 ±0.39) to (5.32±0.43), with significant difference between the two groups (t=23.480, P < 0.001). After 4 weeks of treatment, the NIBUT of the experimental group increased from (5.19 ±1.12) s to (9.36 ±1.47) s, and that of the control group increased from (5.21± 1.04) s to (7.18 ±1.25) s (t = 6.188, P<0.001). The proportion of thin tear film lipid layer in experimental group was significantly lower than that in control group (all P<0.05); The clinical symptoms of the eyes in both groups of patients decreased after treatment, and the experimental group was lower than the control group (both P<0.05). Conclusion: Pre operative dry eye comprehensive treatment can improve dry eye symptoms and tear film stability of cataract patients with diabetes from multiple dimensions, and provide an effective plan for perioperative management of cataract patients.
