Research progress on animal model of mixed infection of microorganisms keratitis
Author:
  • Yu-Ting Li

    Yu-Ting Li

    Department of Ophthalmology, Affiliated Hospital of Yunnan University;Department of Ophthalmology, the Second Peoples Hospital of Yunnan Province;Yunnan Eye Hospital;Department of Ophthalmology, Fourth Affiliated Hospital of Kunming Medical University;Yunnan Eye Institute;Yunnan Clinical Medical Research Center of Eye Diseases;Yunnan Clinical Medical Center of Eye Diseases;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, Yunnan Province, China
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  • Yan Li

    Yan Li

    Department of Ophthalmology, Affiliated Hospital of Yunnan University;Department of Ophthalmology, the Second Peoples Hospital of Yunnan Province;Yunnan Eye Hospital;Department of Ophthalmology, Fourth Affiliated Hospital of Kunming Medical University;Yunnan Eye Institute;Yunnan Clinical Medical Research Center of Eye Diseases;Yunnan Clinical Medical Center of Eye Diseases;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, Yunnan Province, China
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  • Lan Wang

    Lan Wang

    Department of Ophthalmology, Affiliated Hospital of Yunnan University;Department of Ophthalmology, the Second Peoples Hospital of Yunnan Province;Yunnan Eye Hospital;Department of Ophthalmology, Fourth Affiliated Hospital of Kunming Medical University;Yunnan Eye Institute;Yunnan Clinical Medical Research Center of Eye Diseases;Yunnan Clinical Medical Center of Eye Diseases;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, Yunnan Province, China
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  • Zhu-Lin Hu

    Zhu-Lin Hu

    Department of Ophthalmology, Affiliated Hospital of Yunnan University;Department of Ophthalmology, the Second Peoples Hospital of Yunnan Province;Yunnan Eye Hospital;Department of Ophthalmology, Fourth Affiliated Hospital of Kunming Medical University;Yunnan Eye Institute;Yunnan Clinical Medical Research Center of Eye Diseases;Yunnan Clinical Medical Center of Eye Diseases;Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Kunming 650021, Yunnan Province, China
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Fund Project:

The Association Foundation Program of Yunnan Province Science and Technology Department and Kunming Medical University \〖No.202001AY070001(-165)\〗

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    Abstract:

    Microbial mixed infectious keratitis is an ocular surface disease caused by corneal infection, which has an acute onset and rapid progression and can lead to blindness in severe cases. Establishing an animal model of microbial mixed infectious keratitis is conducive to exploring its pathogenesis, prevention, clinical diagnosis and treatment. This article reviews the methods of making animal models of mixed infectious keratitis with microorganisms and the diagnostic methods after successful modelling infections, aiming to provide references for the further development and research of animal models of the disease.

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Yu-Ting Li, Yan Li, Lan Wang,/et al.Research progress on animal model of mixed infection of microorganisms keratitis. Guoji Yanke Zazhi( Int Eye Sci) 2022;22(2):230-234

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Publication History
  • Received:May 24,2021
  • Revised:December 21,2021
  • Online: January 27,2022