Research progress of erythropoietin in the treatment of diabetic retinopathy
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National Natural Science Foundation of China(No.81570852)

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    Abstract:

    Diabetic retinopathy(DR)is the most common complication of diabetes mellitus and remains the leading cause of blindness in working-age population. DR affects almost all the retinal cells, leading to the disruption and dysfunction of neurovascular unit and the neural-glial network. Erythropoietin(EPO), a glycoprotein hormone, plays a pivotal role in neuroprotection, neurotrophy, anti-inflammation, anti-apoptosis and anti-oxidation etc., in various central nervous system diseases. This review discussed the protective effect of EPO in DR so as to provide new options for DR treatment.

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Dan-Dan Liu, Guo-Tong Xu, Jing-Fa Zhang. Research progress of erythropoietin in the treatment of diabetic retinopathy. Guoji Yanke Zazhi( Int Eye Sci) 2021;21(9):1539-1542

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Publication History
  • Received:November 01,2020
  • Revised:July 28,2021
  • Adopted:
  • Online: August 18,2021
  • Published: