Recent advances in research on delayed corneal epithelial wound healing in diabetes

doi:10.3980/j.issn.1672-5123.2020.8.15

Home > Archive>Volume 20, Issue 8, 2020 >1367-1370. DOI:10.3980/j.issn.1672-5123.2020.8.15

Recent advances in research on delayed corneal epithelial wound healing in diabetes
DOI:
                        10.3980/j.issn.1672-5123.2020.8.15
                    
Author:
                        Yan-Ni WuYan-Ni Wu
Department of Ophthalmology,the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
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Qi ZhangQi Zhang
Department of Ophthalmology,the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
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Fund Project:Joint Project of Health Bureau with Science and Technology Bureau of Chongqing(No.2019MSXM003); Basic Research program of Chongqing Natural Science Foundation Project(No.cstc2019jcyj-msxmX0398)

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Abstract:

Delayed healing of diabetic corneal epithelial wound is a commonly encountered condition, and persistent corneal epithelial defects may give rise to recurrent epithelium erosion, corneal ulceration, and subsequent perforation as well as affecting visual loss. The current review focused on the pathological basis, updates of the pathogenesis, and recent advances in the treatment of delayed healing of diabetic corneal epithelial wounds, wherein the roles of hyperglycemia, tear film, proteases, cytokines, corneal nerves and genes were elaborated, and the latest views on treatment strategies, for the delayed healing were summarized as well. Recent advances in research on delayed corneal epithelial wound healing in diabetes mellitus.

Key words:diabetes mellitus; corneal epithelium; delayed wound healing

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Yan-Ni Wu, Qi Zhang. ,/et al.Recent advances in research on delayed corneal epithelial wound healing in diabetes. Guoji Yanke Zazhi( Int Eye Sci) 2020;20(8):1367-1370

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Publication History

Received:December 04,2019
Revised:June 28,2020
Adopted:
Online: July 22,2020
Published:

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