Home > Archive>Volume 16, Issue 10, 2016 >1894-1897. DOI:10.3980/j.issn.1672-5123.2016.10.27
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Retinal blood supply changes after vitrectomy combined with panretinal photocoagulation in PDR patients with anterior segment neovascularization
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    Abstract:

    AIM: To investigate hemodynamic alterations of retrobulbar vessels in proliferative diabetic retinopathy(PDR)patients with anterior segment neovascularization, before and 3mo after vitrectomy combined with panretinal photocoagulation and to explore the clinical significance.

    METHODS: Color Doppler flow imaging(CDFI)was used for measurement of blood flow velocities and resistive indexes(RI)of the ophthalmic artery(OA), short posterior ciliary arteries(sPCA)and central retinal artery(CRA)in 21 eyes of 21 PDR patients with anterior segment neovascularization. CDFI parameters were obtained before and 3mo after vitrectomy combined with panretinal photocoagulation(PRP).

    RESULTS: Peak systolic velocity(PSV)and end diastolic velocity(EVD)of CRA were significantly increased after surgeries, RI were decreased significantly(P<0.05). Parameters of sPCA and OA have no change after surgeries(P>0.05).

    CONCLUSION: Vitrectomy combined with panretinal photocoagulation might increase the velocity of CRA, decrease RI and improve ocular blood supply postoperatively. It may delay or prevent the process of neovascular glaucoma.

    Reference
    1杨新光,朱赛琳,解晓明.疑难青光眼的诊断与治疗.北京:人民军医出版社 2005:106-107
    2 Neudorfer M,Kessner R,Goldenberg D,et al. Retrobulbar blood flow changes in eyes with diabetic retinopathy: a 10-year follow-up study. Clin Ophthalmol 2014; 8:2325-2332
    3 Hamanaka T,Akabane N, Yajima T,et al.Retinal ischemia and angle neovascularization in proliferative diabetic retinopathy. Am J Ophthalmol 2001; 132(5):648-658
    4 Shiba T,Takahashi M,Hori Y,et al. Relationship between sleep-disordered breathing and iris and/or angle neovascularization in proliferative diabetic retinopathy cases. Am J Ophthalmol 2011; 151(4):604-609
    5刘晓玲,孙心铨.重视糖尿病视网膜病变以及眼底病激光光凝的规范化治疗.中华眼底病杂志2010; 26(2):16-17
    6 Silva PS,Cavallerano JD,Haddad NM,et al.Peripheral lesions Identified on Ultrawide Field Imaging Predict Increased Risk of Diabetic Retinopathy Progression over 4 Years. Ophthalmology 2015; 122(5):949-956
    7 Terasaki H,Miyake Y,Mori M, et al.Fluorescein angiography of extreme peripheral retina and rubeosis iridis in proliferative diabetic retinopathy. Retina 1999; 19(4):302-308
    8 Zhou M,Chen S,Wang W,et al.Levels of erythropoietin and vascular endothelial growth factor in surgery-required advanced neovascular glaucoma eyes before and after intravitreal injection of bevacizumab. Invest Ophthalmol Vis Sci 2013; 54(6):3874-3879
    9 Wanger J, Danser A, Perkx F, et al. Demonstration of renin mRNA, angiotensinogen mRNA, and angiotensin converting enzyme mRNA expression in the human eye:evidence for an intraocular renin-angiotensin system.Br J Ophthalmol 1996; 80(2):1591
    10 Watanabe D,Suzuma K,Suzuma I, et al. Vitreous levels of angiopoietin 2 and vascular endothelial growth factor in patients with proliferative diabetic retinopathy. Am J Ophthalmol 2005; 139(3):476-481
    11 Takagi H,Koyama S,Seike H,et al. Potential role of the angiopoietin/tie2 system in ischemia-induced retinal neovascularization.Invest Ophthalmol Vis Sci 2003; 44(1):393-402
    12 Forooghian F,Kertes PJ,Eng KT,et al. Alterations inthe intraocular cytokine milieu after intravitreal bevacizumab. Invest Ophthalmol Vis Sci 2010; 51(5):2388-2392
    13 Kuiper EJ, Van Nieuwenhoven FA, de Smet MD, et al. The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy. PLoS One 2008; 3(7):e2675
    14 Arevalo JF,Maia M,Flynn HW Jr, et al.Tractionai retinal detachment following intravitreal bevacizumab(Avastin)in patients with severe proliferative retinopathy.Br J Ophthalmol 2008; 92(2):213-216
    15王友,邓铂林,黄健,等.玻璃体腔注射雷珠单抗治疗严重增生型糖尿病视网膜病变后玻璃体细胞因子的变化.中华眼底病杂志 2014; 30(5): 484-487
    16 Molnar I,Poitry S,Tsacopoulos M, et al.Effect of laser photocoagulation on oxygenation of the retina in miniature pigs. Invest Ophthalmol Vis Sci 1985; 26(10):1410-1414
    17刘豪杰,周明,邵彦.激光光凝治疗增殖期糖尿病视网膜病变.中国实用眼科杂志 2006; 24(2):167-168
    18张惠蓉.眼底病激光治疗.北京: 人民卫生出版社 2012:58
    19吕永顺,鲍永珍,黎晓新,等. 氩激光视网膜光凝治疗增殖型糖尿病视网膜病变的疗效.中华眼底病杂志 1995; 11(4):227-228
    20钟一声,朱益华.新生血管性眼病.第1版.北京:人民军医出版社2006:432-56
    21孙心铨,王燕琪,敖丽君,等.激光全视网膜光凝术激光量和疗效的临床分析. 中华眼底病杂志1997; 19(4): 195-196
    22梁建宏,Irene Barbazetto.内层视网膜从玻璃体腔摄取氧的初步研究.眼科研究 2004; 22(2):173-176
    23 Stefánsson E,Novack RL,Hatchell DL.Vitrectomy prevents retinal hypoxia in branch retinal vein occlusion.Invest Ophthalmol Vis Sci 1990; 31(2):284-289
    24 Helbig H, Kellner U, Bornfeld N,et al. Rubeosis iridis after vitrectomy for diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol 1998; 236(10):730-733
    25 Stalmans I, Vandewalle E, Anderson DR, et al. Use of colour Doppler imaging in ocular blood flow research.Acta Ophthalmol 2011; 89(8):e609-630
    26 Dimitrova G, Kato S. Color Doppler imaging of retinal diseases. Surv Ophthalmol 2010; 55(3):193-214
    27 Jimenez-aragon F,Garcia-martin E,Larrosa-lopez R,et al. Role of color doppler imaging in early diagnosis and prediction of progression in glaucoma. Biomed Res Int 2013; 2013:871689
    28 Garhöfer G,Fuchsjäger-Mayrl G,Vass C, et al. Retrobulbar blood flow velocities in open angle glaucoma and their association with mean arterial blood pressure. Invest Ophthalmol Vis Sci 2010; 51(12):6652-6657
    29鲁平,鲁豫,袁建军,等.彩色多普勒超声观察糖尿病视网膜病变视网膜血流动力学变化.中国超声医学杂志2004; 20(9):657
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Yong Wang, Xing-Dong Shi, Bo-Jie Hu,/et al.Retinal blood supply changes after vitrectomy combined with panretinal photocoagulation in PDR patients with anterior segment neovascularization. Guoji Yanke Zazhi( Int Eye Sci) 2016;16(10):1894-1897

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Publication History
  • Received:June 23,2016
  • Revised:September 01,2016
  • Online: September 19,2016
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