Abstract:AIM: To analyze the expression of apoptosis factor in cataract and age-related cataract lens epithelial cells.
METHODS: A total of 50 cases(50 eyes)of concurrent silicone oil cataract patients as study group and the same period of 50 cases(50 eyes)of age-related cataract patients as control group were selected in our hospital during Mar. 2014 to Mar. 2016. In the determination of two groups of patients had been accurately grasped the specific content of the research program and signed informed consent book of the lens epithelial cells apoptosis factor expression. They were measured and compared.
RESULTS: Study group of Bcl-2 protein expression positive rate was 92%. Bax protein expression positive rate was 100%. The expression of caspase-3 protein expression positive rate was 100%. Compared with the control group, the expression of bcl-2 expression positive rate of 80%. Bax protein expression positive rate of 84%. Caspase-3 protein expression positive rate of 82%. Difference between the two groups were statistically significant(P<0.05).
CONCLUSION: Concurrent silicone oil cataract lens epithelial cells apoptosis factor expression is significantly higher than that of age-related cataract. A clinical lens epithelial cells apoptosis factors of full participation in the silicone oil cataract extraction in the development and progression is prompted.
