Investigation and analysis of bacterial spectrum and drug sensitivity test in conjunctival sac of cataract patients of Kazak

Abstract:

ATM: To analyze bacterial spectrum and drug sensitivity in conjunctival sac of cataract patients of Kazak.

METHODS:A total of 538 cases of conjunctival sac secretion in cataract patients of Kazak were collected. The samples were cultured and their sensibilities to antibiotics were tested.

RESULTS: The bacterial culture was positive in 214 cases. The positive rate was 39.8%. The variety of pathogenic bacteria were mainly made up of gram positive cocci(88.3%), and most of them were Staphylococcus epidermidis(66.4%), followed by Micrococcus(9.8%). Sex had no effect on conjunctival bacteria rate in the cataract patients of Kazak, while age, place of residence had an effect on camier rate. The camier rate of conjunctival bacteria was significantly higher in people over 60 years old than that in people with age between 40 to 59 years old. And the people from city had a significant lower bacteria positive rate than those from countryside and pastoral. Most of grams were sensitive to Vancomycin, Teicoplanin, Rifampicin, Duly cloth mildew mutual and Amikacin, the tolerance was less than 20%, and they usually had higher tolerance to Penicillin, Erythromycin, Tetracycline and Chloramphenicol(>70%).

CONCLUSION: Gram positivecocci is the most common bacteria in conjunctival sac in cataract patients of Kazak. Staphylococcus epidermidis was most common, followed by Micrococcus. The germ-carrying rate of conjunctival SAC in Kazakh population is associated with the patient's age and area of residence. The clinical use of antibacterial drugs should be strictly grasp the indications, to reduce the incidence of bacterial resistance.

Key words:Kazakh; cataract; conjunctival sac; bacterial; drug sensitivity test