Lan Li
Department of Ophthalmology, the First Peoples Hospital of Kunming, Kunming 650011,Yunnan Province, ChinaYu-Lin Liang
Department of Ophthalmology, the First Peoples Hospital of Kunming, Kunming 650011,Yunnan Province, ChinaYun-Chuan Li
Department of Ophthalmology, the First Peoples Hospital of Kunming, Kunming 650011,Yunnan Province, ChinaEducation Department Foundation of Yunnan Province, China(No.2010c101)
AIM: To observe the clinical effect subconjunctival bevacizumab and triamcinolone acetonide(TA)on corneal neovascularization(CNV)induced by penetrating keratoplasty.
METHODS: Nineteen patients(20 eyes)with CNV induced by penetrating keratoplasty after 3mo were selected and were divided into 4 groups randomly: Group A was control group, group B was treated by subconjunctival of bevacizumab(2.5mg, 0.1mL), group C was treated by subconjunctival of bevacizumab(2.5mg, 0.1mL)and TA(4mg, 0.1mL), group D was treated by subconjunctival of TA(4mg, 0.1mL), one time each month, twice.
RESULTS: The average follow-up period was 3a. Visual acuity of groups B and C kept stable or increase slightly. CNV and immunologic rejection were lighten(P<0.01), symptomatic of ophthalmalgia and photophobia relief synchronous.
CONCLUSION: Treatment of subconjunctival bevacizumab and TA can effectively inhibite CNV and immunologic rejection, also has the therapeutical effect to maintain implant transparence after penetrating keratoplasty.
Lan Li, Yu-Lin Liang, Yun-Chuan Li. ,/et al.Prevent effect of Bevacizumab and Triamcinolone acetonide on corneal neovascularization induced by penetrating keratoplasty. Guoji Yanke Zazhi( Int Eye Sci) 2014;14(11):2016-2018
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