Expression and meaning of Bcl-2 and MMP-9 in pterygium
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Hubei Provincial Health Department Funded Project(No.JX5B17)

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    Abstract:

    ATM:To study the expression and the relationship of B-cell lymphoma/leukemia-2 (Bcl-2 )and matrix metalloproteinases-9(MMP-9) in pterygium, and to provide the theory basis for the treatment of pterygium.METHODS:The expression of Bcl-2 and MMP-9 were detected in 76 cases with pterygium by immunohistochemical method and were compared with the normal conjunctiva epithelium in other 9 cases.RESULTS:The expression of Bcl-2 and MMP-9 was higher in pterygium than in normal conjunctiva epithelium(P<0.05).The expression of Bcl-2 was related to that of MMP-9.CONCLUSION:The increase of Bcl-2 and MMP-9 are presented in pterygium, which may play an important role in the origin and development of pterygium .

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Dan-Na Zhang, Gui-Fang Yang, Zhao-Chen Liu. Expression and meaning of Bcl-2 and MMP-9 in pterygium. Guoji Yanke Zazhi( Int Eye Sci) 2012;12(9):1729-1730

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Publication History
  • Received:February 16,2012
  • Revised:August 13,2012
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