Abstract:AIM:To compare the central corneal thickness(CCT) measured by Lenstar LS900 and SIRIUS anterior segment analysis system.METHODS:The CCT was measured on 29 patients (58 eyes), aged 18 to 40 years old, using Lenstar LS900 and SIRIUS eye anterior segment analysis system respectively before the refractive operation. A paired t-test comparison has been taken. The linear regression analysis was used to analyze the correlation of the two measurement results. Bland-Altman has been taken to analyze the correlation of the two methods.RESULTS:The average value of CCT with Lenstar LS900 was 532.89±46.65μm, and that of SIRIUS measurement was 532.10±47.21μm. Two kinds of measurements showed no significant difference (P>0.05). Correlation coefficient analysis showed high correlation. The correlation coefficient was 0.994 (P<0.05). Two kinds of the measurements of CCT were consistent.CONCLUSION:The measurement results of Lenstar LS900 and SIRIUS eye anterior segment analysis system show high uniformity. Two measuring instruments are precise and can be used to measure CCT.