Abstract:AIM:To observe the effect of horizontal strabismus surgery on the intraocular pressure(IOP)so as to offer evidence for further exploring the correlation between the change of anterior segment blood flow and IOP.METHODS:Forty-six cases 70 eyes received horizontal strabismus surgery,and were divided into two groups.55 eyes underwent one horizontal rectus muscle surgery,15 eyes underwent two horizontal rectus muscle surgery.All surgical eyes were measured by NCT Canon TX-F at five time stages:preoperative 1-2 day;1 day,1 week,1 month,3 months after operation.Then two groups samples data were analyzed with ANOVA.RESULTS:In the group of one horizontal rectus muscle surgery there were no significant differences between the IOP of preoperation and 1 day postoperatively;preoperation and 1 week postoperatively;while there was significant difference between the IOP of preoperation and 1 month postoperatively(P=0.016);there was significant difference between the IOP of preoperation and 3 months postoperatively(P=0.006).In the group of two horizontal retus muscle surgery the IOP of preoperation had no significant differences with that of 1 day postoperatively,1 week postoperatively,1 month postoperatively and 3 months postoperatively.CONCLUSION:The IOP of eyes undergone horizontal rectus strabismus surgery has a slight rise in both groups,then it gradually decreases.Those of 3 months postoperation are lowest in five time stages.In the group of one horizontal rectus strabismus surgery,there are significant differences between the IOP of preoperation and 1 month postoperatively;preoperation and 3 months postoperatively.