Meta-analysis on changes of tear film and tear secretion after phacoemulsification for cataract

Abstract:

·AIM:To evaluate changes of tear film and tear secretion after phacoemulsification for cataract.·METHODS:Six articles published from January 2000 to August 2009 were retrieved through the following databases:PubMed,Web of knowledge,CNKI,Chinese Bio-medicine Database along with Google web search and manual retrieval.Relative difference(RD)between preoperative and 3-month-postoperative tear film break-up time(BUT)and Schirmer Ⅰ test(S Ⅰ t)were set as the effect indexes.The data of these articles were evaluated with Meta-analysis by random model.·RESULTS:At 3-month-postoperative time,the BUT value was significantly lower than the preoperative value[weighted average value of RD is 1.34 with 95% confidence interval(CI)in(0.40,2.30),P=0.01],but the SⅠt value did not differ from preoperative value significantly[weighted aver-age value of RD is 0.80,95% CI is(-0.14,1.75),P=0.10].·CONCLUSION:At 3-month-postoperative time,the stability of tear film has not recovered yet,but the tear secretion has recovered to preoperative level in eyes underwent phacoemulsification surgery for cataract.·

Key words:phacoemulsification;tear;Meta-analysis