Childhood myopia in the modern environment: modifiable risk factors and evidence-based prevention
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Hua Gao. Eye Hospital of Shandong First Medical University (Shandong Eye Hospital), Jinan 250021, Shandong Province, China. hgao@sdfmu.edu.cn

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Supported by the National Natural Science Foundation of China (No.82571179[CRISPR]; No.82371032); the Major Basic Research Project of the Natural Science Foundation of Shandong Province (No.ZR2023ZD60); the Taishan Scholar Program (No.tstp20231255).

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    Abstract:

    This review aimed to summarize modifiable environmental and lifestyle risk factors for childhood myopia and evaluate evidence-based preventive strategies for family, school, and public health practice. Following the PRISMA-ScR framework, relevant studies on children aged 5–18y published up to January 2026 were retrieved from mainstream databases, and eligible literature was synthesized according to study design and evidence level. Reduced outdoor activity, excessive near-work and screen exposure, urban residence, insufficient sleep, and gene-environment interaction are major risk factors for childhood myopia. Daily outdoor activity of 1–2h or longer confers protective effects via promoting retinal dopamine release and inhibiting axial elongation, whereas prolonged close work and excessive screen time notably elevate myopia risk. Optimizing outdoor time, regulating ocular use habits, ensuring sufficient sleep, and implementing school-based interventions are core evidence-based preventive measures, and wearable devices and objective biomarkers can facilitate behavioral management and intervention evaluation. In conclusion, childhood myopia is influenced by multiple adjustable factors; increased outdoor exposure is the most effective preventive measure, and combined behavioral and policy interventions are essential to curb the global prevalence of childhood myopia and prevent subsequent severe visual complications.

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Farheen Tariq, Shi-Long Huang, Bing-Xin Ren, et al. Childhood myopia in the modern environment: modifiable risk factors and evidence-based prevention. Int J Ophthalmol, 2026,(9):1847-1857

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Publication History
  • Received:February 22,2026
  • Revised:May 21,2026
  • Adopted:
  • Online: August 14,2026
  • Published: