Exosomes in ocular graft-versus-host disease: an overview
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Lu-Sheng Ma and Yuan-Feng Zhang. Yantai Yuhuangding Hospital, Qingdao University, Yantai 264000, Shandong Province, China. mls138545002448@163.com; yuanfengzhang126@126.com

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    Abstract:

    Ocular graft-versus-host disease (oGVHD) is an immune disease that occurs in the eye after allogeneic hematopoietic stem cell transplantation and seriously affects the vision and quality of life of patients. Current treatment modalities are inadequate, and new treatment options and targets are required to improve the therapeutic efficacy of oGVHD. In recent years, a large number of studies have shown that exosomes, as important mediators of cell-to-cell communication, have important research value in the pathogenesis, diagnosis, and treatment of oGVHD. This article reviews the research progress on exosomes from different sources of oGVHD.

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Xiao-Han Jin, Xin-Xin Yu, Mei-Qi Fan, et al. Exosomes in ocular graft-versus-host disease: an overview. Int J Ophthalmol, 2026,(8):1629-1642

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Publication History
  • Received:October 28,2025
  • Revised:February 10,2026
  • Adopted:
  • Online: July 15,2026
  • Published: