Early changes in corneal densitometry after FS-LASIK combined with accelerated corneal cross-linking for correction of high myopia
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Peng Ji and Hong-Sheng Bi. 48 Yingxiong Mountain Road, Shizhong District, Jinan 250002, Shandong Province, China. ji6605@126.com; hongshengbi1@163.com

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Supported by Shandong Province Medical Staff Science and Technology Innovation Program Project (No.SDYWZGKCJH2022021).

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    Abstract:

    AIM: To observe the effects of femtosecond laser-assisted excimer laser in situ keratomileusis combined with accelerated corneal cross-linking (FS-LASIK Xtra) on corneal densitometry after correcting for high myopia. METHODS: In this prospectively study, 130 patients underwent FS-LASIK or FS-LASIK Xtra for high myopia. Their right eyes were selected for inclusion in the study, of which 65 cases of 65 eyes in the FS-LASIK group, 65 patients with 65 eyes in the FS-LASIK Xtra group. Patients were evaluated for corneal densitometry at 1, 3, and 6mo postoperatively using Pentacam Scheimpflug imaging. RESULTS: Preoperative differences in corneal densitometry between the FS-LASIK and FS-LASIK Xtra groups in different ranges were not statistically significant (P>0.05). Layer-by-layer analysis revealed statistically significant differences in the anterior (120 μm), central, and total layer corneal densitometry between the FS-LASIK and FS-LASIK Xtra groups at 1 and 3mo postoperatively (all P<0.05), the FS-LASIK Xtra group is higher than that of the FS-LASIK group. Analysis of different diameter ranges showed statistically significant differences between the FS-LASIK group and the FS-LASIK Xtra group at 1mo postoperatively in the ranges of 0–2, 2–6, and 6–10 mm (both P<0.05); At 3mo postoperatively, the FS-LASIK Xtra group is higher than that of the FS-LASIK group in the ranges of 0–2 and 2–6 mm (P<0.05). At 6mo postoperatively, there were no statistically significant differences in corneal densitometry between the FS-LASIK group and the FS-LASIK Xtra group in different diameter ranges (all P>0.05). CONCLUSION: There is an increase in internal corneal densitometry during the early postoperative period after FS-LASIK Xtra for correction of high myopia. However, the densitometry values decreased to the level of conventional FS-LASIK at 6mo after surgery, with the most significant changes observed in the superficial central zone.

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Qing-Bao Wang, Hong-Sheng Bi, Xiao-Fan Wang, et al. Early changes in corneal densitometry after FS-LASIK combined with accelerated corneal cross-linking for correction of high myopia. Int J Ophthalmol, 2024,17(7):1307-1312

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Publication History
  • Received:November 03,2023
  • Revised:February 20,2024
  • Adopted:
  • Online: June 25,2024
  • Published: