Assessment of tear film parameters post-treatment with commercial eyelid cleaning wipes: a pilot study
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Amal Aldarwesh. Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia. aaldarweesh@ksu.edu.sa

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    Abstract:

    AIM: To investigate the short-term effects of commercially available eyelid-cleaning wipes on film parameters. METHODS: This study enrolled 48 healthy participants aged 20-35y (both males and females). Clinical assessment included the Ocular Surface Disease Index (OSDI) questionnaire, non-invasive tear break-up time (NITBUT), tear meniscus height (TMH), and lipid layer pattern (LLP). Based on these initial results, participants were categorized as either non-dry eye or dry eye. Participants in each group were randomly allocated to either Blephaclean® or Systane® treatments. Changes in NITBUT, TMH, and LLP levels before and after lid wipe treatment were assessed. RESULTS: The dry eye group exhibited significantly higher OSDI scores and lower NITBUT and TMH levels than in the non-dry eye group (P<0.001). Following the application of eyelid wipes (Systane® wipes), dry eye subjects experienced a significant improvement in NITBUT levels (P=0.0014) compared to the non-dry eye individuals. Although the remaining participants showed a marginal increase in TMH and NITBUT levels, these changes did not achieve statistical significance (P>0.05). Similarly, the LLP levels were significantly improved with Systane® (P<0.001) post-treatment compared to individuals in the non-dry eye group. However, the dry eye subjects showed higher post-treatment LLP levels than the untreated group (P<0.02). CONCLUSION: The short-term effects of Systane® eyelid wipes on tear film parameters suggest their effectiveness in dry eye disease. Nonetheless, further exploration of their long-term impact is essential to justify their cost effectiveness and efficacy in treating both aqueous deficiency and evaporative dryness.

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Amal Aldarwesh, Ali Almustanyir, Raied Fagehi, et al. Assessment of tear film parameters post-treatment with commercial eyelid cleaning wipes: a pilot study. Int J Ophthalmol, 2024,17(4):659-664

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Publication History
  • Received:August 30,2023
  • Revised:January 17,2024
  • Adopted:
  • Online: March 26,2024
  • Published: