Progress in exosomes and their potential use in ocular diseases
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Feng Wang and Ying Su. Ophthalmology Branch of the First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China. wangfd@126.com; hyingsu@126.com

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Supported by the National Natural Science Foundation of China (No.81470633); the Natural Science Grant of the Heilongjiang Province of China (No.H2018035); the Innovation and Development Foundation of the First Affiliated Hospital of Harbin Medical University (No.2018L002).

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    Abstract:

    Exosomes contain a variety of biological active substances such as proteins, miRNAs, lncRNAs and lipids, and exosomes from different cells play different biological functions. Exosomes, as a carrier, are involved in many pathological processes such as nerve injury and repair, vascular regeneration, immune response, and fibrosis formation. It plays an important role in the treatment of eye diseases such as glaucoma, diabetic retinopathy, and keratitis. This paper reviews the research progress of exosomes in various diseases in vivo, which provides a new way for the treatment of eye diseases.

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Su-Fang Li, Ying Han, Feng Wang, et al. Progress in exosomes and their potential use in ocular diseases. Int J Ophthalmol, 2020,13(9):1493-1498

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Publication History
  • Received:November 04,2019
  • Revised:April 15,2020
  • Adopted:
  • Online: August 20,2020
  • Published: