Corneal graft melting: a systematic review
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Xiu-Ming Jin. Eye Center, the Affiliated Second Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. lzyjxm@zju.edu.cn

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Supported by National Natural Science Foundation of China (No.81870558; No.81870624; No.81700802); Major Science and Technology Projects of Zhejiang Province (No.2017C03046).

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    Abstract:

    Corneal graft melting is a severe complication of keratoplasty. This review is to summarize the incidence, the pathogenesis, the risk factors, the prognosis and the prevention of corneal graft melting after keratoplasty. We systematically searched PubMed, Web of Science and WanFang database to retrieve potentially eligible articles about relevant clinical reports and animal experiments. We read the full texts to identify eligible articles. The selection of studies and data extraction were performed independently by two reviewers. In conclusion, the pathogenesis of corneal graft melting is complicated, and many risk factors are closely related to corneal graft melting. Analysis of pathogenesis and risk factors of corneal graft melting can facilitate the development of targeted therapies to better guide clinical practice.

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Bin-Bin Zhu, Jie Zhou, Jiao Zheng, et al. Corneal graft melting: a systematic review. Int J Ophthalmol, 2020,13(3):493-502

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Publication History
  • Received:October 25,2018
  • Revised:December 20,2019
  • Adopted:
  • Online: February 04,2020
  • Published: