Myopia genetics in genome-wide association and post-genome-wide association study era
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Xuan Liao and Chang-Jun Lan. Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China. aleexand@163.com; eyelanchangjun@163.com

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Supported by Projects of Science & Technology Department of Sichuan Province (No.2019YJ0381).

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    Abstract:

    Genome-wide association studies (GWAS) of myopia and refractive error have generated exciting results and identified novel risk-associated loci. However, the interpretation of the findings of GWAS of complex diseases is not straightforward and has remained challenging. This review provides a brief summary of the main focus on the advantages and limitations of GWAS of myopia, with potential strategies that may contribute to further insight into the genetics of myopia in the post-GWAS or omics era.

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Xuan Liao, Qing-Qing Tan, Chang-Jun Lan. Myopia genetics in genome-wide association and post-genome-wide association study era. Int J Ophthalmol, 2019,12(9):1487-1492

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Publication History
  • Received:October 05,2018
  • Revised:May 21,2019
  • Adopted:
  • Online: August 02,2019
  • Published: