Renal function and choroidal thickness using swept-source optical coherence tomography in diabetic patients
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Antonio Manuel Garrido-Hermosilla. Department of Ophthalmology, Virgen Macarena University Hospital, 3 Doctor Fedriani Avenue, Seville 41009, Spain. gaherfamily@hotmail.com

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OFTARED “RD16/0008/0010”, funded by Instituto de Salud Carlos III, integrated in the national I+D+i 2013-2016 and co-funded by European Union (ERDF/ESF, “Investing in your future”)

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    Abstract:

    AIM: To assess the relationship between choroidal thickness and renal function in diabetic patients. METHODS: Cross-sectional retrospective clinical study of 42 eyes of 21 ocular treatment-naïve diabetic patients. Demographic data included: age, sex, type and course of diabetes. Ocular data included: severity of diabetic retinopathy; retinal thickness at the central macular region, as well as choroidal thickness at the central and paracentral quadrants, using automatically generated maps by swept-source optical coherence tomography; presence of cystic macular edema; and ocular axial length (AXL). Lab-test parameters included: glycated hemoglobin (HbA1c), albuminuria, albumin/creatinine ratio in urine, and glomerular filtration rate. RESULTS: A significant negative correlation was mainly observed between several choroidal thicknesses, age (P<0.020) and ocular AXL (P<0.030). On the contrary, a significant positive correlation was found between all choroidal thicknesses, HbA1c (P<0.035) and albuminuria (P<0.040). CONCLUSION: Choroidal thickness can represent an additional tool to help clinicians predicting the renal status in ocular treatment-naïve diabetic patients.

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Antonio Manuel Garrido-Hermosilla, Mariola Méndez-Muros, Estanislao Gutiérrez-Sánchez, et al. Renal function and choroidal thickness using swept-source optical coherence tomography in diabetic patients. Int J Ophthalmol, 2019,12(6):985-989

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Publication History
  • Received:October 09,2018
  • Revised:November 26,2018
  • Adopted:
  • Online: May 06,2019
  • Published: