Ex-PRESS implantation with phacoemulsification in POAG versus CPACG
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Li-Xin Xie. Qingdao Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao 266071, Shandong Province, China. lixin_xie@hotmail.com

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Supported by the Key Laboratory Program of Shandong Eye Institute (No.2014-1); Medicine Science and Technology Development Program, Shandong, China (No.2015WS0204); the Science and Technology plan of Qingdao, China (No.15-9-1-35-jch); the Innovation Project of Shandong Academy of Medical Sciences.

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    Abstract:

    AIM: To compare the long-term outcomes of the Ex-PRESS miniature glaucoma device implanted under a scleral flap in combination of phacoemulsification with intraocular lens implantation in primary open angle glaucoma (POAG) and chronic primary angle-closure glaucoma (CPACG). METHODS: Retrospective, comparative study. A total of 60 eyes (60 patients) receiving the Ex-PRESS miniature glaucoma device implantation combined with phacoemulsification were reviewed. Thirty eyes (30 patients) had the combined procedures for POAG, and the other 30 eyes (30 patients) for CPACG. RESULTS: The follow-up was 39.37±7.09mo (range 3 to 49mo) in patients with POAG and 37.10±9.26mo (range 9 to 49mo) in patients with CPACG (P=0.29). The mean change in best corrected visual acuity was 0.41 logMAR for POAG and 0.38 logMAR for CPACG at the last follow-up (P=0.22). The postoperative intraocular pressure (IOP) of the POAG group was significantly lower than the CPACG group at 1, 3, 12, and 18mo after surgery (P=0.02, 0.00, 0.04, 0.01) with similar glaucoma medications after surgery (P>0.16). At 3y after surgery, the cumulative complete and qualified success rates were 63.3% (POAG) and 53.3% (CPACG), 83.3% (POAG) and 73.3% (CPACG) (P=0.41, 0.49), respectively. The POAG group had more hypotony than the CPACG group (P=0.04). CONCLUSION: The long-term outcomes show the Ex-PRESS implantation combined with phacoemulcification can effectively lower the IOP in both the POAG and CPACG groups. The POAG group seems to have lower postoperative IOP and a higher risk of hypotony.

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Jie Lan, Da-Peng Sun, Jie Wu, et al. Ex-PRESS implantation with phacoemulsification in POAG versus CPACG. Int J Ophthalmol, 2017,10(1):51-55

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Publication History
  • Received:March 18,2016
  • Revised:April 25,2016
  • Adopted:
  • Online: January 04,2017
  • Published: