Effect of focal laser photocoagulation in eyes with mild to moderate non-proliferative diabetic retinopathy
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Jung Il Han. Department of Ophthalmology, Kim’s Eye Hospital, Myung-Gok Eye Research Institute, Konyang University College of Medicine, Seoul 07301, Korea. han66139@kimeye.com

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    Abstract:

    AIM: To report the effect of focal laser photocoagulation on both the severity of hard exudates (HEs) and the rate of disease progression in eyes with mild to moderate non-proliferative diabetic retinopathy (NPDR). METHODS: We retrospectively reviewed the medical records of 33 patients (60 eyes) who had been diagnosed with mild to moderate NPDR between January 2006 and December 2012. The patients were divided into 2 groups: Group A (38 eyes in 20 patients treated using focal laser photocoagulation) and Group B (treated without laser photocoagulation). We also reviewed the best corrected visual acuity measurements, and the fundus photographs taken at both baseline and follow-up visits. RESULTS: In Group A, HE severity grade had decreased significantly from baseline to the final visit (P<0.05), but this was not the case in Group B (P=0.662). The cumulative probabilities of retinopathy progression at 5y were 26% in Group A and 30% in Group B. Kaplan-Meier survival curves showed no significant difference between the groups with regard to retinopathy progression (P=0.805). CONCLUSION: Focal laser photocoagulation reduced the levels of HEs in eyes with mild to moderate NPDR. However, the treatment was not able to decelerate the progression of DR.

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Seong Hun Jeong, Jung Il Han, Sung Won Cho, et al. Effect of focal laser photocoagulation in eyes with mild to moderate non-proliferative diabetic retinopathy. Int J Ophthalmol, 2016,9(10):1439-1443

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Publication History
  • Received:March 16,2016
  • Revised:April 19,2016
  • Adopted:
  • Online: October 13,2016
  • Published: