Femtosecond laser-assisted deep anterior lamellar keratoplasty for keratoconus and keratectasia
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Department of Ophthalmology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210002, Jiangsu Province, China

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Supported by National Natural Science Foundation of China (No. 81270979); Natural Science Foundation of Jiangsu Province, China (No.BK2012777).
Conflicts of Interest: Lu Y, None; Shi YH, None; Yang LP, None; Ge YR, None; Chen XF, None; Wu Y, None; Huang ZP, None

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    Abstract:

    AIM: To describe the initial outcomes and safety of femtosecond laser-assisted deep anterior lamellar keratoplasty (DALK) for keratoconus and post-LASIKkeratectasia.METHODS:In this non-comparative case series, 10 eyes of 9 patients underwent DALK procedures with a femtosecond laser (Carl Zeiss Meditec AG, Jena, Germany). Of the 9 patients, 7 had keratoconus and 2 had post-LASIK keratectasia. A 500 kHz VisuMax femtosecond laser was used to perform corneal cuts on both donor and recipient corneas.The outcome measures were the uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), corneal thickness, astigmatism, endothelial density count (EDC), and corneal power.RESULTS: All eyes were successfully treated. Early postoperative evaluation showed a clear graft in all cases. Intraoperative complications included one case of a small Descemet’s membrane perforation. Postoperatively, there was one case of stromal rejection, one of loosened sutures, and one of wound dehiscence. A normal corneal pattern topography and transparency were restored, UCVA and BCVA improved significantly, and astigmatism improved slightly. There was no statistically significant decrease in EDC.CONCLUSION: Our early results indicate that femtosecond laser-assisted deep anterior lamellar keratoplasty could improve UCVA and BCVA in patients with anterior corneal pathology. This approach shows promise as a safe and effective surgical choice in the treatment of keratoconus and post-LASIK keratectasia.

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Yan Lu, Yu-Hua Shi, Li-Ping Yang, et al. Femtosecond laser-assisted deep anterior lamellar keratoplasty for keratoconus and keratectasia. Int J Ophthalmol, 2014,7(4):638-643

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Publication History
  • Received:December 20,2013
  • Revised:March 04,2014
  • Adopted:March 04,2014
  • Online: August 15,2014
  • Published: