Characteristics of the macula in amblyopic eyes by optical coherence tomography
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Supported by Key Projects in the Medicine Health Science and Technology from Guangzhou, China (No.201102A211005); Fundamental Research Funds of State Key Laboratory of Ophthalmology, China

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    Abstract:

    AIM: To test the hypothesis that amblyopic neuroretina may have an altered thickness when compared to the normal. METHODS: Twenty-five amblyopic, young patients between the ages of 7 and 11 years old were studied. The interested neuroretina areas are defined into 10 sub-regions according to superior-inferior, nasal-temoral, and peri-para axis, which cross the fovela structure. The thicknesses of ten, defined macular regions were separately measured by optical coherence tomography (OCT) and analyzed by t-test. RESULTS: The average thickness of neuroretina in the exact foveola of the amblyopic eyes is larger than that of normal eyes (P<0.05), but the other nine regions have no significant difference. Interestingly, in both the normal and amblyopic eyes, the temporal area looks thinner than other quadrants (P<0.05). CONCLUSION: Thickness alteration may be associated with amblyopic disorders in young patients. Studying a larger volume of subjects of similar age is required to confirm this observation.

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Xin-Mei Wang, Dong-Mei Cui, Ling Zhen, et al. Characteristics of the macula in amblyopic eyes by optical coherence tomography. Int J Ophthalmol, 2012,5(2):172-176

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Publication History
  • Received:November 24,2011
  • Revised:March 29,2012
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