Abstract:AIM: To study the results and complications of LASIK surgery after radial keratotomy. METHODS: This descriptive study was carried out in Yazd LASIK Center, Yazd, Iran. Cases included all patients who had been operated between April 2003 and September 2006. Data were collected via a special questionnaire and analyzed by SPSS software and paired t-test. RESULTS: Samples included 33 eyes of 23 patients of whom 11 (47.8%) were women and 12 (52.2%) were men. Their age ranged from 28 to 49 years old and the mean age was 31.6 years old. Two cases (6.1%) had openings of the previous radial keratotomy incisions during flap lifting and one case (3%) had moderate non-infectious keratitis. The mean preoperative spherical equivalent (SE) was -2.17D±0.94SD, while the postoperative SE was -0.17D±0.19SD, the difference of which was significant (P =0.0001). Mean preoperative uncorrected visual acuity (UCVA) was 0.07±0.02SD (logMAR) and the postoperative was 0.880.16SD (log MAR), the difference of which was also significant (P=0.0001). The mean best spectacle corrected visual acuity prior to the operation was 0.930.08SD (log MAR) and 0.920.08SD (logMAR) after the operation, the difference of which was not significant (P=0.268). CONCLUSION: LASIK surgery could improve residual myopia after the radial keratotomy without major complications during or post operation, but necessity of the second procedure must be pondering and require careful case selection and assessment.