Abstract:Objective: To investigate the efficacy of pars plana vitrectomy (PPV) with or without inner limiting membrane (ILM) peeling on refractory macular edema in diabetes. Methods: Eighty patients with refractory macular edema in diabetes were retrospectively selected and assigned into groups according to the treatment method. Among them, 38 patients treated with PPV were included as group A, and 42 patients treated with PPV combined with ILM peeling were included as group B. The relevant data of patients in the two groups were collected and the efficacy of the two groups was compared. Results: At 1, 3, and 6 months after surgery, the best corrected visual acuity (BCVA), central macular retinal thickness (CMT), and severity of macular edema in group B were all superior to those in group A (P<0.05). After surgery, the incidence of complications in group B was 11.90%, with no prominent difference compared to group A's 18.42% (P>0.05). Conclusion: PPV combined with or without ILM peeling can improve visual function and relieve macular edema in patients with refractory macular edema in diabetes. However, the combination of PPV and ILM peeling is superior to PPV alone in improving vision and relieving macular edema, and does not increase postoperative complications.
