[关键词]
[摘要]
眼眶周围痛是干眼常见伴发症状，痛觉信号经三叉神经眼支传导，临床以灼热、胀痛、刺痛为典型表现，严重影响患者生活质量。西医与中医针对干眼相关眼眶周围痛的干预各有优势，西医起效迅速、靶点明确，中医整体辨证、远期复发率更低。西医治疗通常包括药物治疗和物理介入治疗等手段，中医治疗包含内服中药、外用中药及针灸推拿等治疗手段。文章将系统梳理近5 a来中西医对干眼相关眼眶周围痛发病机制的认识及现有的中西医治疗研究进展，同时总结当前研究局限，旨在为干眼相关眼眶周围痛的规范化临床诊疗提供参考与启发。
[Key word]
[Abstract]
Periorbital pain is a common concomitant symptom of dry eye disease, which is transmitted through the ophthalmic branch of the trigeminal nerve and mainly manifests as burning, distending, and stinging sensations, severely impairing patients' quality of life. Western medicine and traditional Chinese medicine have unique advantages in managing dry eye-related periorbital pain. Western medicine can rapidly relieve targeted symptoms, while traditional Chinese medicine adopts holistic syndrome differentiation to lower long-term recurrence risk. Western therapeutic modalities include pharmacotherapy and physical interventional therapies, and Chinese medicine interventions cover oral herbal formulas, topical herbal preparations, acupuncture and Tuina massage. This paper systematically reviews advances over the past five years regarding the pathogenesis of dry eye-associated periorbital pain and integrated traditional Chinese and western therapeutic schemes. The limitations of current clinical studies are summarized, aiming to offer standardized clinical references and innovative insights for the diagnosis and management of dry eye-induced periorbital pain.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(No.82074495); 上海市东方英才计划拔尖项目(No.2024DFYC)
