[关键词]
[摘要]
目的:观察合并无症状黄斑前膜的白内障患者超声乳化术后黄斑区厚度的变化。
方法:前瞻性研究。收集2023年8月至2025年8月本院收治的合并无症状黄斑前膜的白内障患者的临床资料。术后随访3 mo,比较手术前后患者最佳矫正视力(BCVA)、黄斑中心凹厚度(CFT)、黄斑中心凹3 mm 区域厚度。
结果:本研究共纳入合并无症状黄斑前膜的白内障患者87例90眼,术后1 mo 失访1例1眼,失访率为1%。完成随访的86例89眼患者中男38例,女48例,平均年龄76.51±5.23岁,眼轴长度为23.32±0.27 mm,核硬度为Ⅲ级以上者85眼(95.5%),术前CFT为344.56±54.13 μm,术前黄斑中心 3 mm 区域厚度为351.25±32.32 μm。术后1 wk,1、3 mo,BCVA均较术前提高(均P<0.05),CFT及黄斑中心凹3 mm 区域厚度均较术前增厚(均P<0.05)。术后1 wk,1眼出现假性囊样黄斑水肿(PCME),经醋酸泼尼松龙滴眼液每日4次点眼和溴芬酸钠滴眼液每日2次点眼,治疗2 mo后,黄斑囊样水肿完全消退,视力恢复到术后的平均水平,无视物变形。
结论:合并无症状黄斑前膜的白内障患者行超声乳化手术安全有效。
[Key word]
[Abstract]
AIM: To observe the changes in macular thickness after phacoemulsification in cataract patients with asymptomatic epiretinal membrane.
METHODS: This was a prospective study. Clinical data of cataract patients with asymptomatic epiretinal membrane treated in the hospital from August 2023 to August 2025 were collected. Patients were followed up for 3 mo postoperatively. Best corrected visual acuity(BCVA), central foveal thickness(CFT), and macular thickness in the central 3 mm area were compared before and after surgery.
RESULTS:A total of 87 patients(90 eyes)with cataract and asymptomatic epiretinal membrane were enrolled. One patient(1 eye)was lost to follow-up at 1 mo postoperatively, with a loss rate of 1%. Among the 86 patients(89 eyes)who completed the follow-up, there were 38 males and 48 females, with a mean age of 76.51±5.23 y. The mean axial length was 23.32±0.27 mm. Eighty-five eyes(95.5%)had nuclear hardness of grade Ⅲ or above. Preoperative CFT was 344.56±54.13 μm, and preoperative macular thickness in the central 3 mm area was 351.25±32.32 μm. At 1 wk, 1 and 3 mo postoperatively, BCVA improved compared with preoperative values(all P<0.05), while CFT and macular thickness in the central 3 mm area increased significantly(all P<0.05). At 1 wk postoperatively, pseudocystoid macular edema(PCME)occurred in one eye. After treatment with prednisolone acetate eye drops 4 times daily and bromfenac sodium eye drops 2 times daily for 2 mo, edema fully resolved, visual acuity recovered to the average postoperative level, and no metamorphopsia was observed.
CONCLUSION: Phacoemulsification is safe and effective for cataract patients with asymptomatic epiretinal membrane.
[中图分类号]
[基金项目]
2023安阳市科技计划项目(No.2023C01SF225)