目的：比较卡尺、Pentacam HR、IOL Master 700、OPD Scan Ⅲ和CIRRUS HD-OCT这五种设备在有晶状体眼人工晶状体(ICL)植入术前测量角膜白到白距离(WTW)的差异及一致性，为ICL植入型号选择提供参考依据。

方法：回顾性研究。纳入2023年11月至2024年6月我院行双眼ICL V4c植入术的高度近视患者。术前分别采用卡尺、Pentacam HR、IOL Master 700、OPD Scan Ⅲ和CIRRUS HD-OCT五种方法测量WTW，比较各仪器测量结果差异及一致性。

结果：本研究共纳入高度近视患者249例498眼，其中男85例170眼，女164例328眼，年龄18-38(平均30.2±5.8)岁。卡尺、Pentacam HR、IOL Master 700、OPD Scan Ⅲ和CIRRUS HD-OCT五种方法WTW测量结果分别为11.24±0.31、11.55±0.35、11.88±0.37、11.69±0.38和11.56±0.41 mm(P<0.05)。除Pentacam HR与CIRRUS HD-OCT间比较无差异外(P>0.05)，其余测量方法间相互比较均有差异(均P<0.05)。各仪器间WTW测量值均呈正相关(均P<0.01)。Bland-Altman分析显示，仅Pentacam HR与OPD Scan Ⅲ、Pentacam HR与CIRRUS HD-OCT、OPD Scan Ⅲ与IOL Master 700 间的95%一致性界限在±0.50 mm以内。

结论：五种仪器测量WTW结果存在系统性差异，其中IOL Master 700 测量值最大、卡尺测量值最小。卡尺测量与其他自动化设备一致性较差，不可替代； Pentacam HR与OPD Scan Ⅲ、CIRRUS HD-OCT，OPD Scan Ⅲ与IOL Master 700间具有较好一致性，可在临床ICL型号选择时互为参考。

METHODS:This retrospective study included high myopia patients who underwent ICL V4c implantation in the hospital between November 2023 and June 2024. Preoperative WTW measurements were obtained using calipers, Pentacam HR, IOL Master 700, OPD Scan Ⅲ, and CIRRUS HD-OCT. Differences and agreement of measurements among the devices were compared.

RESULTS:A total of 249 high myopia patients(498 eyes)were enrolled in this study, including 85 males(170 eyes)and 164 females(328 eyes). The patients' age ranged from 18 to 38 y, with a mean age of 30.2±5.8 y. The mean WTW values measured by calipers, Pentacam HR, IOL Master 700, OPD Scan Ⅲ, and CIRRUS HD-OCT were 11.24±0.31, 11.55±0.35, 11.88±0.37, 11.69±0.38, and 11.56±0.41 mm, respectively. No significant difference was found between Pentacam HR and CIRRUS HD-OCT(P>0.05), while significant differences were observed among all other measurement method pairs(P<0.05). All measurement methods showed significant positive correlations(P<0.01). Bland-Altman analysis demonstrated that only the comparison between Pentacam HR and OPD Scan Ⅲ, Pentacam HR and CIRRUS HD-OCT, and OPD Scan Ⅲ and IOL Master 700 had 95% limits of agreement within ±0.50 mm.

CONCLUSION:Systematic differences exist among the five devices in measuring WTW, with IOL Master 700 yielding the largest value and caliper the smallest. Caliper measurements demonstrate poor agreement with automated devices and should not be considered interchangeable. In contrast, Pentacam HR, OPD Scan Ⅲ, and CIRRUS HD-OCT, OPD Scan Ⅲ and IOL Master 700 demonstrate relatively good agreement and may serve as alternative references for ICL sizing in clinical practice.