[关键词]
[摘要]
颈动脉狭窄(CAS)可显著影响眼部血流动力学，导致视网膜、脉络膜及视神经等多部位缺血性损害。通过颈动脉超声、磁共振血管造影等多模影像技术，可准确评估CAS程度。中重度CAS与眼缺血综合征、视网膜动静脉阻塞、视网膜结构改变(如缺血性血管周围病变、神经纤维层变薄、视网膜下玻璃状沉积)、缺血性视神经病变及脉络膜血流改变等密切相关。颈动脉内膜剥脱术和支架成形术可改善眼部灌注，缓解缺血症状，但术后需警惕视网膜动脉栓塞等并发症。文章就CAS与眼底缺血性疾病的研究进展进行综述。
[Key word]
[Abstract]
Carotid artery stenosis(CAS)can significantly impair ocular hemodynamics, resulting in ischemic injury involving the retina, choroid, and optic nerve. The severity of CAS can be accurately evaluated using multimodal imaging techniques, including carotid ultrasonography and magnetic resonance angiography. Moderate to severe CAS is closely associated with ocular ischemic syndrome, retinal arterial and venous occlusions, retinal structural alterations(such as retinal ischemic perivascular lesions, thinning of the retinal nerve fiber layer, and subretinal drusenoid deposits), ischemic optic neuropathy, and changes in choroidal blood flow. Carotid endarterectomy and carotid artery stenting may improve ocular perfusion and alleviate ischemic manifestations; however, postoperative complications such as retinal artery embolism require careful monitoring. This review summarizes recent advances in the understanding of the relationship between CAS and ocular ischemic diseases.
[中图分类号]
[基金项目]
无锡市“双百”中青年医疗卫生拔尖人才培养计划(No.BJ2023037); 中国健康促进基金会科研发展公益项目(No.2025-ZCXY-0455)
