[关键词]
[摘要]
视网膜静脉阻塞(RVO)是我国第二大视网膜血管性疾病，常伴有全身性心脑血管疾病，脂代谢异常是RVO重要的危险因素之一。脂代谢异常通过血管内皮损伤、血流动力学异常、氧化应激及炎症反应等病理机制多途径驱动RVO进展，与黄斑水肿和新生血管形成等并发症相关。文章系统综述脂代谢异常在RVO发病机制及其临床意义，通过分析血脂指标与RVO的关联，旨在加强针对原发疾病及全身危险因素的管理，为脂代谢异常的早期全身综合干预RVO提供理论依据。
[Key word]
[Abstract]
Retinal vein occlusion(RVO)is the second most common retinal vascular disease in China and is frequently accompanied by systemic cardiovascular and cerebrovascular disorders. Dyslipidemia serves as a key risk factor for RVO. Dyslipidemia drives the progression of RVO through multiple pathological mechanisms, including vascular endothelial injury, hemodynamic abnormalities, oxidative stress, and inflammatory responses. It is also closely associated with complications such as macular edema and neovascularization. This review systematically summarizes current research on the role of dyslipidemia in the pathogenesis of RVO and its clinical significance. By analyzing the associations between lipid profile indicators and RVO, this article aims to emphasize the importance of managing primary diseases and systemic risk factors, and to provide a theoretical basis for early comprehensive systemic interventions targeting dyslipidemia in patients with RVO.
[中图分类号]
[基金项目]
广东省医学科研基金项目(No.B2023401)
