[关键词]
[摘要]
糖尿病患者白内障术后继发黄斑水肿是影响术后视力的重要并发症,其既与糖尿病患者本身存在的微血管病变、炎症反应等病理基础密切相关,也受到白内障手术引发的眼部组织创伤、术后炎症应激等因素的影响。文章综述相关发病机制,总结分析两者的叠加机制主要体现在炎症反应的放大、血管活性因子的失衡及血流循环障碍,以期为临床该类患者的防治提供理论依据。
[Key word]
[Abstract]
Secondary macular edema following cataract surgery in diabetic patients is a major complication that impairs postoperative visual acuity. It is not only closely associated with the pathological basis including microvascular lesions and inflammatory responses intrinsic to diabetic patients, but also influenced by factors such as ocular tissue trauma and postoperative inflammatory stress induced by cataract surgery. This review summarizes the relevant pathogenesis and analyzes that the superposition mechanism of these two factors is mainly manifested by the amplification of inflammatory reactions,the imbalance of vasoactive factors,and impaired blood circulation,aiming to provide a theoretical basis for the prevention and management of this complication in such patients in clinical settings.
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[基金项目]
北京市中医药科技发展资金项目(No.BJZYYB-2023-57); 北京市自然科学基金资助项目(No.7232325); 中国中医科学院眼科医院高水平中医医院课题(No.GSP4-02-4)