目的：评估非衍射型景深延长型人工晶状体(EDOF IOL)在高度近视并发白内障(HMC)患者中的术后临床效果。

方法：回顾性分析2022年1月至2024年12月于我院诊断为HMC的临床资料，将患者按植入IOL类型分为观察组(行FLACS联合非衍射型EDOF IOL植入)与对照组(行FLACS联合非球面单焦点IOL植入)。比较两组术后视力(LogMAR)、视觉质量、满意度。

结果：本研究最终纳入患者33例47眼，其中观察组10例17眼，对照组23例30眼。观察组年龄59.0(52.8，63.8)岁，男8例13眼，女2例4眼。对照组年龄56.0(53.5，60.0)岁，男13例17眼，女10例13眼。术后3 mo，观察组与对照组最佳矫正远视力分别为0.10(0.08，0.12)和0.20(0.10，0.40)(P=0.586)。但观察组最佳矫正中视力\〖0.10(0.10，0.10)vs 0.50(0.40，0.90)，P=0.032\〗和最佳矫正近视力\〖0.20(0.18，0.20)vs 0.60(0.45，1.45)，P=0.044\〗显著优于对照组。离焦曲线显示，观察组在-2.00-+1.00 D范围内裸眼视力比较平缓，优于对照组。术后问卷调查表明，观察组脱镜率(76%)和总体满意度(88%)显著高于对照组(10%和60%)。

结论：非衍射型EDOF IOL通过扩展焦深显著改善中近视力，减少眼镜依赖，同时维持远视力，为HMC患者提供了更优的术后视觉质量和生活满意度。

METHODS:A retrospective analysis was conducted on the clinical data of patients diagnosed with HMC at the hospital from January 2022 to December 2024. Patients were divided into an observation group \〖undergoing femtosecond laser-assisted cataract surgery(FLACS)combined with non-diffractive EDOF IOL implantation\〗 and a control group(undergoing FLACS combined with aspheric monofocal IOL implantation)according to the type of implanted IOL. Postoperative visual acuity(LogMAR), visual quality, and patient satisfaction were compared between the two groups.

RESULTS: A total of 33 patients(47 eyes)were finally included in this study, including 10 patients(17 eyes)in the observation group and 23 patients(30 eyes)in the control group. The observation group had a median age of 59.0(52.8, 63.8)y, with 8 males(13 eyes)and 2 females(4 eyes). The control group had a median age of 56.0(53.5, 60.0)y, with 13 males(17 eyes)and 10 females(13 eyes). At 3 mo postoperatively, the best-corrected distance visual acuity(BCDVA)was 0.10(0.08, 0.12)in the observation group and 0.20(0.10, 0.40)in the control group(P=0.586). However, the best-corrected intermediate visual acuity(BCIVA)\〖0.10(0.10, 0.10)vs 0.50(0.40, 0.90), P=0.032\〗 and best-corrected near visual acuity(BCNVA)\〖0.20(0.18, 0.20)vs 0.60(0.45, 1.45), P=0.044\〗 in the observation group were significantly better than those in the control group. The defocus curve showed that the uncorrected visual acuity(UCVA)in the observation group was relatively stable within the range of -2.00 to +1.00 D, which was superior to that in the control group. Postoperative questionnaires showed that the spectacle independence rate(76%)and overall satisfaction(88%)in the observation group were significantly higher than those in the control group(10% and 60%, respectively).

CONCLUSION: Non-diffractive EDOF IOL significantly improves intermediate and near visual acuity, reduces spectacle dependence, and maintains distance visual acuity by extending the depth of focus, providing better postoperative visual quality and life satisfaction for HMC patients.