目的：评价80岁及以上老年人双眼植入区域折射型多焦点人工晶状体的视觉功能和光学质量。

方法：采用单中心前瞻性非随机对照临床研究，根据患者(80岁及以上白内障患者)个人偏好，接受双眼植入LS-313 MF30或CT Asphina 409MP。术后评估包括矫正及未矫正的远、中、近视力，以及离焦曲线。使用视觉功能问卷(VF-14)、脱镜率和患者满意度调查进行主观评估，分析眩光、光晕和星芒等光干扰现象。

结果：与409MP组(13例26眼，85.77±2.20岁)相比，MF30组(8例16眼，85.38±2.56岁)在矫正和未矫正的中、近视力方面表现更优，而远视力在两组之间相当。MF30组的离焦曲线在0.00 D和3.00 D处有两个峰值，表明焦深更广。MF30组患者具更高的脱镜率和满意度。虽然眩光(28.% vs 18.5%，P=0.584)、星芒(9.5% vs 3.7%，P=0.567)和光晕(23.8% vs 11.11%，P=0.438)在MF30组中更常见但它们通常较轻，并不显著影响日常活动。

结论：区域折射型多焦点人工晶状体为80岁及以上老年患者提供更好的远近视觉、更高的脱镜率和满意度。尽管MF30的光干扰现象更常见，但它们通常较轻，并不显著影响日常活动。

METHODS: A single-center, non-randomized, prospective clinical trial was conducted, involving cataract patients aged 80 y and older. Patients received bilateral implantation of the LS-313 MF30 or CT Asphina 409MP, based on personal preference. Postoperative assessments included uncorrected and corrected visual acuity at distance, intermediate, and near ranges, as well as defocus curve. Subjective evaluations were performed using the visual function(VF-14)questionnaire, spectacle independence rates, and patient satisfaction surveys. Photic phenomena such as glare, halos, and starbursts were also analyzed.

RESULTS: The MF30 group(16 eyes from 8 participants, 85.38±2.56 y)exhibited superior uncorrected and corrected intermediate and near visual acuity compared to the 409MP group(26 eyes from 13 participants, 85.77±2.20 y), while distance visual acuity was comparable between groups. The defocus curve of the MF30 group revealed two peaks at 0.00 D and -3.00 D, indicating a broader depth of focus. Patients in the MF30 group reported higher rates of spectacle independence and greater satisfaction. While photic phenomena such as glare(28.6% vs 18.5%, P=0.584), starburst(9.5% vs 3.7%, P=0.567)and halos(23.8% vs 11.11%, P=0.438)were more prevalent in the MF30 group, they were generally mild and did not significantly impact daily activities.

CONCLUSION: Zonal refractive multifocal IOLs provide elderly patients with improved distance and near vision, greater spectacle independence, and greater satisfaction. Although photic phenomena were slightly more frequent with MF30, they are generally reported as non-disruptive and do not affect their daily life compared to monofocal IOLs.