目的：探讨无缝线角膜缘干细胞移植手术联合角膜绷带镜治疗翼状胬肉的临床疗效。

方法：回顾性收集2020年1月至2025年1月医院收治的翼状胬肉患者，根据治疗方式不同分为A组(采用无缝线角膜缘干细胞移植手术联合角膜绷带镜治疗)和B组(采用单纯无缝线角膜缘干细胞移植手术治疗)。比较两组术后不同时间点角膜上皮完全修复愈合情况、眼部舒适度、角膜屈光状态，记录两组术后并发症发生情况。

结果：本研究共纳入翼状胬肉患者120例120眼，其中A组60例60眼，B组60例60眼。A组年龄51.88±5.22岁，男33例，女27例。B组年龄52.48±6.00岁，男30例，女30例。术后1、2 wk，A组角膜上皮完全修复愈合率高于B组(均P<0.05)。两组术后1、2 wk眼部舒适度评分均较术后当天降低，且A组各时间点评分低于B组(均P<0.05)。术后1、3 mo，两组角膜地形图表面不对称指数(SAI)、角膜散光度(CA)、角膜表面规则指数(SRI)均较术前减小，且A组各时间点低于B组(均P<0.05)。A组术后各并发症发生率略低于B组，但差异无统计学意义(均P>0.05)。

结论：无缝线角膜缘干细胞移植手术联合角膜绷带镜治疗可促进翼状胬肉患者术后角膜上皮愈合，增加术后短期眼部舒适度，同时能促进术后短期角膜屈光状态改善，并在一定程度上减少术后并发症的发生。

METHODS: A retrospective collection was conducted on patients with pterygium admitted to the hospital from January 2020 to January 2025. They were divided into two groups according to different treatment methods. Group A received seamless corneal limbal stem cell transplantation surgery combined with bandage soft contact lens, while group B received simple seamless corneal limbal stem cell transplantation surgery. The complete repair and healing of corneal epithelium, ocular comfort and corneal refractive status at different time points after surgery were compared between the two groups, and the occurrence of postoperative complications in the two groups was recorded.

RESULTS: This study included 120 cases(120 eyes)of patients with pterygium, including 60 cases(60 eyes)in the group A and 60 cases(60 eyes)in the group B. Group A had an age of 51.88±5.22 years, with 33 males and 27 females. Group B had an age of 52.48±6.00 years, with 30 males and 30 females. The complete repair and healing rate of corneal epithelium in the group A was higher than that in the group B at 1 and 2 wk after surgery(all P<0.05). At 1 and 2 wk after surgery, the scores of the eye comfort assessment table in both groups decreased compared to the day of surgery, and the group A was lower than the group B at all time points(all P<0.05). At 1 and 3 mo after surgery, the surface asymmetry index(SAI), corneal astigmatism(CA), and corneal surface regularity index(SRI)of the corneal topography in both groups decreased compared to preoperative values, and the group A was lower than the group B at all time points(all P<0.05). The incidence of postoperative complications in the group A was slightly lower than that in the group B, but the difference was not statistically significant(all P>0.05).

CONCLUSION: The seamless corneal limbal stem cell transplantation surgery combined with bandage soft contact lens treatment can promote postoperative corneal epithelial healing in patients with pterygium, increase short-term eye comfort after surgery, improve short-term corneal refractive status after surgery, and reduce the occurrence of postoperative complications to a certain extent.