目的：探讨高度近视白内障患者术后人工晶状体偏心倾斜对高阶像差(HOAs)的影响。

方法：回顾性分析我院收治的高度近视白内障患者100例100眼，均给予超声乳化术+人工晶状体植入术治疗，术后3 mo进行随访，应用Pentacam三维眼前段分析仪测量人工晶状体的倾斜度与偏心量，使用i Trace像差仪采集患者在3.0 mm与5.0 mm瞳孔下的HOAs。采用Pearson线性分析人工晶状体偏心倾斜与HOAs的相关性。

结果：患者术后人工晶状体的倾斜度为1.49°±0.32°，偏心量为0.33±0.05 mm，倾斜度与偏心量呈正相关。在瞳孔直径为3 mm或5 mm时，术后人工晶状体的倾斜度与总HOAs(r=0.351，P=0.003； r=0.287，P=0.015)、总彗差(r=0.389，P=0.002； r=0.332，P=0.005)成正相关性，而与总球差(r=0.382，P=0.235； r=0.149，P=0.207)无明显相关性。人工晶状体的偏心值与总HOAs(r=0.011，P=0.930； r=-0.146，P=0.215)、总彗差(r=0.023，P=0.856； r=-0.102，P=0.393)、总球差(r=0.085，P=0.476； r=-0.165，P=0.162)均无明显相关性。

结论：高度近视白内障患者术后人工晶状体的倾斜会对总HOAs、总彗差造成影响，从而影响患者术后视力。

METHODS: Totally 100 patients(100 eyes)with high myopic cataract were retrospectively analyzed and treated with phacoemulsification and intraocular lens implantation. Then follow up was conducted 3 mo after surgery. The Pentacam 3D anterior segment analyzer was used to measure the tilt degree and decentration value of intraocular lens. The i-Trace aberration analyzer was used to collect HOAs from patients under 3.0 mm and 5.0 mm pupils. Pearson linearity was used to analyze the correlation of the decentration tilt of intraocular lens with HOAs.

RESULTS: The tilt degree was 1.49°±0.32°, decentration value was 0.33±0.05 mm, and the tilt degree was positively related to decentration value of intraocular lens. When the pupil diameter was 3 mm or 5 mm, the postoperative tilt degree of intraocular lens was positively related to total HOAs(r=0.351, P=0.003; r=0.287, P=0.015)and total coma(r=0.389, P=0.002; r=0.332, P=0.005), while not correlated with total spherical aberration(r=0.382, P=0.235; r=0.149, P=0.207). In addition, the decentration value of intraocular lens not correlated with total HOAs(r=0.011, P=0.930; r=-0.146, P=0.215), total coma(r=0.023, P=0.856; r=-0.102, P=0.393), and total spherical aberration(r=0.085, P=0.476; r=-0.165, P=0.162).

CONCLUSION: The tilt of intraocular lens in high myopic cataract patients after surgery can affect total HOAs and total coma, thereby affecting their postoperative vision.