[关键词]
[摘要]
早发性近视指13岁之前发生近视。其早期进展快、未来发展为高度近视的风险显著升高,已成为威胁儿童视觉健康的重大公共卫生问题。早期诊断与系统性干预是延缓屈光进展、降低高度近视及相关眼底并发症风险的关键窗口期,对改善儿童长期视觉预后具有重要意义。文章旨在系统梳理早发性近视的最新进展,重点围绕早发性近视的遗传与环境交互作用机制、治疗技术研究进展、综合防控策略的创新等方面展开。系统整合了早发性近视治疗相关基础研究与临床实践的最新成果,为早发性近视精准诊疗、公共卫生政策制定及技术创新提供理论支撑,同时也可作为眼科医生、科研人员及政策制定者的重要借鉴。
[Key word]
[Abstract]
Early-onset myopia refers to myopia that develops before the age of 13. Characterized by rapid initial progression and a significantly increased risk of developing high myopia in the future, it has become a major public health problem threatening children's visual health. Early diagnosis and systematic intervention represent a critical window for slowing refractive progression and reducing the risk of high myopia and associated ocular fundus complications, holding significant importance for improving long-term visual outcomes in children. This review aims to systematically summarize recent advances in early-onset myopia, focusing on the mechanisms of gene-environment interactions, advances in treatment technologies, and innovations in comprehensive management strategies. It integrates the latest achievements from both basic research and clinical practice related to the treatment of early-onset myopia, aiming to provide theoretical support for precise diagnosis and treatment, public health policy formulation, and technological innovation. Furthermore, it serves as a valuable reference for ophthalmologists, researchers, and policy makers.
[中图分类号]
[基金项目]
宁夏回族自治区中央引导地方科技发展专项项目(No.2024FRD05068)