目的：基于CiteSpace对2014年1月至2024年1月中医药治疗糖尿病视网膜病变(DR)的文献进行可视化分析。方法：基于CNKI数据库检索文献，采用Note Express和CiteSpace软件对文献的年发文量、作者、研究机构、关键词进行共现、聚类、突现分析，绘制知识图谱。结果：共纳入643篇中文文献，年发文量呈现波动趋势，研究机构以辽宁中医药大学、中国中医科学院眼科医院为主； 形成了糖尿病、中医药、综述等20个高频关键词和芪明颗粒、数据挖掘等突现关键词； 2014年开始重点在治疗方法探索及对中成药疗效的关注； 2016-2018研究视角向症状及多因素分析扩展； 2018-2020年对证型和疾病阶段深入研究，2019年后突显中医特色疗法和以患者为中心理念； 2022-2024年研究方法创新及中医络脉理论成为新热点。结论：中医药治疗DR的研究目前仍处于上升阶段，研究热点主要集中在芪明颗粒的应用，未来发展趋势聚焦于疗效评价及作用机制探索。若能够结合不同疗法的联合应用并开展长期随访的临床研究，将有望为循证医学提供更充分的证据支持，进一步挖掘中医药潜力，推动其在DR防治领域的创新发展。

AIM: To conduct a CiteSpace-based visualization analysis of the literature on traditional Chinese medicine(TCM)treatment of diabetic retinopathy(DR)from January 2014 to January 2024.METHODS: The literatures were retrieved from the China National Knowledge Infrastructure(CNKI)database. Co-occurrence, clustering, and emergence analyses of annual publications, authors, research institutions, and keywords were performed using Note Express and CiteSpace software to generate knowledge graph.RESULTS: A total of 643 Chinese-language articles were included. The annual publication trend was characterized by fluctuations. The primary research institutions were Liaoning University of Traditional Chinese Medical and Eye Hospital China Academy of Chinese Medical Sciences. Twenty high-frequency keywords were identified, including diabetes, TCM, and review, along with emergent terms such as Qiming granules and data mining. The research focus in 2014 was on exploring therapeutic methods and the efficacy of proprietary Chinese medicines. From 2016 to 2018, the research perspective expanded to include symptoms and multi-factorial analysis. Between 2018 and 2020, there was an in-depth investigation into evidence types and disease stages. After 2019, the emphasis shifted towards TCM-specific therapies and patient-centered concepts. From 2022 to 2024, innovation in research methods and the theory of TCM collaterals theory emerged as new hotspots.CONCLUSION: The research on TCM treatment for DR is still in an ascending phase. The primary research hotspot currently centers on Qiming granules. Future trends are likely to focus on the efficacy and mechanisms of action. The combined application of different therapies and long-term follow-up experimental research could provide a more robust basis for evidence-based medicine, unearth the potential of TCM, and promote its development in the prevention and treatment of DR.

国家自然科学基金资助项目(No.82360955); 甘肃省科技计划项目(No.23JRRA1250)